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p63 Antibodies

Santa Cruz Biotechnology, Inc. offers a broad range of p63 antibodies. Select p63 antibodies from several monoclonal and/or polyclonal p63 antibodies listed below. View detailed p63 antibody specifications by linking to the specific product blocks. Select appropriate p63 antibodies for your research by isotype, epitope, applications and species reactivity. p63 gene silencer products in siRNA, shRNA Plasmid and shRNA Lentiviral Particle formats are also available.

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p63 (D-9)sc-25268mouse IgG2a15-151 (h)WB, IP, IF, IHC(P), ELISAm, r, h8
p63 (H-137)sc-8343rabbit IgG15-151 (h)WB, IP, IF, IHC(P), ELISAm, r, h28
p63 (S-16)sc-25039goat IgGN-terminal (m)WB, IF, IHC(P), ELISAm, r, h2
p63α (C-12)sc-5301mouse IgG2b513-641 (h)WB, IP, IF, IHC(P), ELISAhuman3
p63α (H-129)sc-8344rabbit IgG513-641 (h)WB, IP, IF, IHC(P), ELISAm, r, h27
p63α (V-20)sc-25040goat IgGC-terminal (m)WB, IP, IF, IHC(P), ELISAm, r, hNEW
p63γ (C-18)sc-8370goat IgGC-terminal (h)WB, IP, IF, ELISAm, r, h4
TA* p63 (D-20)sc-8608goat IgGN-terminal (m)WB, IF, ELISAm, r, h8
ΔN p63 (N-16)sc-8609goat IgGN-terminal (m)WB, IF, ELISAm, r, h15

The following p63 antibodies have been discontinued and replaced by the recommended antibodies above. For detection of all p63 isoforms, p63 (D-9) is the recommended monoclonal antibody and p63 (H-137) is the recommended polyclonal antibody for each of these discontinued antibodies. In particular, p63 (D-9) and p63 (H-137) are the recommended substitutes for p63 (4A4).

Discontinued Products: p63 (4A4): sc-8431; p63 (87C553): sc-56187; p63 (BC4A4): sc-56188; p63 (SPM208): sc-56457; p63 (3F306): sc-71825; p63 (3F307): sc-71826; p63 (0.N.498): sc-7827; p63 (4H221): sc-71828.

p63 siRNA, shRNA Plasmid and shRNA Lentiviral Particles gene silencers include:

siRNAsshRNA PlasmidsshRNA Lentiviral ParticlesCITATIONSRANKING
p63 siRNA (h): sc-36161p63 shRNA Plasmid (h):
p63 shRNA (h)
Lentiviral Particles: sc-36161-V
p63 siRNA (m): sc-36162p63 shRNA Plasmid (m):
p63 shRNA (m)
Lentiviral Particles: sc-36162-V

Transcription factor p63 is a widely expressed nuclear protein that exists as twelve isoforms and is a member of the p53 gene family. Alternate promoters encode two main variants, TAp63 and ΔNp63, which are further spliced into at least five isoforms, designated α, β, γ, δ and ε, due to alternative splicing events at the carboxy-terminus. TAp63 is transcribed from an upstream promoter containing a similar transactivation domain to p53, while ΔNp63 is transcribed from a promoter located on intron 3, that results in a unique transactivation domain and distinct biological functions. Considered to be oncogenic, ΔNp63 is required for cell growth and survival and can be dominant-negative over TAp63 and p53. TAp63 can transactivate some p53 target genes and is primarily responsible for tubulogenesis and cyst formation.