Welcome to Santa Cruz Biotechnology!

OASL Antibodies

Santa Cruz Biotechnology, Inc. offers a broad range of OASL antibodies. Select OASL antibodies from several monoclonal and/or polyclonal OASL antibodies listed below. View detailed OASL antibody specifications by linking to the specific product blocks. Select appropriate OASL antibodies for your research by isotype, epitope, applications and species reactivity. OASL gene silencer products in siRNA, shRNA Plasmid, shRNA Lentiviral Particle and CRISPR/Cas9 Knockout Plasmid formats are also available.

Introducing HOVERcruz™,

a unique system for rapid identification of OASL Antibodies. Hover over product names in the table to see representative data for each product.

Live chat is now available! (click here)

Our live chat system is available to answer your product and ordering questions.

Also see additional OASL Antibodies including, OASL1

PRODUCT NAMECAT. #ISOTYPEEPITOPEAPPLICATIONSSPECIESCITATIONSRATING
OASL (H-200)sc-98313rabbit IgG1-200 (h)WB, IP, IF, ELISAhuman
OASL (N-12)sc-107831goat IgGN-terminal (h)WB, IP, IF, ELISAh, e
OASL (T-14)sc-107832goat IgGN-terminal (h)WB, IF, ELISAhuman
OASL (L-25)sc-130832rabbit IgGN/AWB, IP, IF, IHC(P), ELISAhuman
OASL1 (M-300)sc-98385rabbit IgG1-300 (m)WB, IP, IF, ELISAm, r

OASL CRISPR/Cas9 Knockout Plasmids include:

PRODUCT NAMECAT. #APPLICATIONSSPECIESCITATIONS
OASL CRISPR/Cas9 KO Plasmid (h)sc-417005gene knockouthumanNEW
Oasl1 CRISPR/Cas9 KO Plasmid (m)sc-433090gene knockoutmouseNEW

OASL siRNA, shRNA Plasmid and shRNA Lentiviral Particles gene silencers include:

siRNAsshRNA PlasmidsshRNA Lentiviral ParticlesCITATIONSRANKING
OASL siRNA (h): sc-95857OASL shRNA Plasmid (h):
sc-95857-SH
OASL shRNA (h)
Lentiviral Particles: sc-95857-V
Oasl1 siRNA (m): sc-150147Oasl1 shRNA Plasmid (m):
sc-150147-SH
Oasl1 shRNA (m)
Lentiviral Particles: sc-150147-V
Not Yet Rated

The 2'-, 5'- oligoadenylate synthetases (OASs) are interferon-induced proteins that play a putative role in mediating resistance to virus infection, control of cell growth, differentiation and apoptosis. OAS1, which functions as a homotetramer, is characterized by its capacity to catalyze the synthesis of 2'-, 5'- oligomers of adenosine (2-5As). OAS1 is also important in evaluating the interferon response in RNAi studies and is implicated in diabetes mellitus susceptibility. OASL1 (2',5'-oligoadenylate synthetase-like 1) is an enzyme that, due to the evolutionary loss of its 2–5A synthetase activity, is suspected to have a novel function independent of 2-5A synthesis. OASL2 has both enzymatic activity and a ubquitin-like domain, acting as a functional intermediate between the active OAS species and the inactive OASL1.