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OASL Antibodies

Santa Cruz Biotechnology, Inc. offers a broad range of OASL antibodies. Select OASL antibodies from several monoclonal and/or polyclonal OASL antibodies listed below. View detailed OASL antibody specifications by linking to the specific product blocks. Select appropriate OASL antibodies for your research by isotype, epitope, applications and species reactivity. OASL gene silencer products in siRNA, shRNA Plasmid, shRNA Lentiviral Particle, CRISPR/Cas9 Knockout and CRISPR Double Nickase Plasmid formats are also available as well as CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems for gene activation.

Introducing HOVERcruz™,

a unique system for rapid identification of OASL Antibodies. Hover over the icon next to the product names in the table to see representative data for that product.

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Our live chat system is available to answer your product and ordering questions.

Also see additional OASL Antibodies including, OASL1

PRODUCT NAMECAT. #ISOTYPEEPITOPEAPPLICATIONSSPECIESCITATIONSRATING
OASL (H-200)
sc-98313rabbit IgG1-200 (h)WB, IP, IF, ELISAhuman
OASL (N-12)
sc-107831goat IgGN-terminal (h)WB, IP, IF, ELISAh, e
OASL (T-14)
sc-107832goat IgGN-terminal (h)WB, IF, ELISAhuman
OASL (L-25)
sc-130832rabbit IgGN/AWB, IP, IF, IHC(P), ELISAhuman
OASL1 (M-300)
sc-98385rabbit IgG1-300 (m)WB, IP, IF, ELISAm, r

OASL CRISPR Knockout, HDR and Nickase Knockout Plasmids include:

PRODUCT NAMECAT. #SPECIESAPPLICATIONSMARKERCITATIONS
OASL CRISPR/Cas9 KO Plasmid (h)
sc-417005humanGene KnockoutGFPNEW
OASL HDR Plasmid (h)
sc-417005-HDRhumanHomology Directed RepairPuromycinNEW
OASL Double Nickase Plasmid (h)
sc-417005-NIChumanGene KnockoutPuromycinNEW
OASL Double Nickase Plasmid (h2)
sc-417005-NIC-2humanGene KnockoutPuromycinNEW
Oasl1 CRISPR/Cas9 KO Plasmid (m)
sc-433090mouseGene KnockoutGFPNEW
Oasl1 HDR Plasmid (m)
sc-433090-HDRmouseHomology Directed RepairPuromycinNEW
Oasl1 Double Nickase Plasmid (m)
sc-433090-NICmouseGene KnockoutPuromycinNEW
Oasl1 Double Nickase Plasmid (m2)
sc-433090-NIC-2mouseGene KnockoutPuromycinNEW

OASL CRISPR Activation Plasmids include:

PRODUCT NAMECAT. #SPECIESAPPLICATIONSMARKERCITATIONS
OASL CRISPR Activation Plasmid (h)
sc-417005-ACThumanGene ActivationZeo, Blast, HygroNEW
OASL CRISPR Activation Plasmid (h2)
sc-417005-ACT-2humanGene ActivationZeo, Blast, HygroNEW
OASL Lentiviral Activation Particles (h)
sc-417005-LAChumanGene ActivationZeo, Blast, HygroNEW
OASL Lentiviral Activation Particles (h2)
sc-417005-LAC-2humanGene ActivationZeo, Blast, HygroNEW
Oasl1 CRISPR Activation Plasmid (m)
sc-433090-ACTmouseGene ActivationZeo, Blast, HygroNEW
Oasl1 CRISPR Activation Plasmid (m2)
sc-433090-ACT-2mouseGene ActivationZeo, Blast, HygroNEW
Oasl1 Lentiviral Activation Particles (m)
sc-433090-LACmouseGene ActivationZeo, Blast, HygroNEW
Oasl1 Lentiviral Activation Particles (m2)
sc-433090-LAC-2mouseGene ActivationZeo, Blast, HygroNEW

OASL siRNA, shRNA Plasmid and shRNA Lentiviral Particles gene silencers include:

PRODUCT NAMECAT. #SPECIESAPPLICATIONSMARKERCITATIONS
OASL siRNA (h)
sc-95857humanGene SilencingN/A
OASL shRNA Plasmid (h)
sc-95857-SHhumanGene SilencingPuromycin
OASL shRNA (h) Lentiviral Particles
sc-95857-VhumanGene SilencingPuromycin
Oasl1 siRNA (m)
sc-150147mouseGene SilencingN/A
Oasl1 shRNA Plasmid (m)
sc-150147-SHmouseGene SilencingPuromycin
Oasl1 shRNA (m) Lentiviral Particles
sc-150147-VmouseGene SilencingPuromycin

The 2'-, 5'- oligoadenylate synthetases (OASs) are interferon-induced proteins that play a putative role in mediating resistance to virus infection, control of cell growth, differentiation and apoptosis. OAS1, which functions as a homotetramer, is characterized by its capacity to catalyze the synthesis of 2'-, 5'- oligomers of adenosine (2-5As). OAS1 is also important in evaluating the interferon response in RNAi studies and is implicated in diabetes mellitus susceptibility. OASL1 (2',5'-oligoadenylate synthetase-like 1) is an enzyme that, due to the evolutionary loss of its 2–5A synthetase activity, is suspected to have a novel function independent of 2-5A synthesis. OASL2 has both enzymatic activity and a ubquitin-like domain, acting as a functional intermediate between the active OAS species and the inactive OASL1.