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NXNL CRISPR Plasmids and si/shRNA Gene Silencers

Santa Cruz Biotechnology, Inc. offers a broad range of gene silencers in the form of siRNAs, shRNA Plasmids and shRNA Lentiviral Particles as well as CRISPR/Cas9 Knockout plasmids. NXNL gene silencers are available as NXNL siRNA, NXNL shRNA Plasmid, NXNL shRNA Lentiviral Particles and NXNL CRISPR/Cas9 Knockout plasmids. NXNL CRISPR/dCas9 Activation Plasmids for gene activation are also available. Gene silencers and activators are useful for gene studies in combination with antibodies used for protein detection.

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PRODUCT NAMECAT. #ISOTYPEEPITOPEAPPLICATIONSSPECIESCITATIONSRATING
NXNL2 (C-17)sc-248125goat IgGInternal (h)WB, IP, IF, ELISAm, r, h
NXNL2 (P-15)sc-248123goat IgGInternal (h)WB, IF, ELISAm, r, h

NXNL CRISPR Knockout and HDR Plasmids include:

PRODUCT NAMECAT. #SPECIESAPPLICATIONSCITATIONSRATING
NXNL2 CRISPR/Cas9 KO Plasmid (h)sc-408554humanGene KnockoutNEWNot Yet Rated
NXNL2 HDR Plasmid (h)sc-408554-HDRhumanHomology Directed RepairNEWNot Yet Rated
NXNL2 CRISPR/Cas9 KO Plasmid (m)sc-429023mouseGene KnockoutNEWNot Yet Rated
NXNL2 HDR Plasmid (m)sc-429023-HDRmouseHomology Directed RepairNEWNot Yet Rated

NXNL CRISPR Activation Plasmids include:

PRODUCT NAMECAT. #SPECIESAPPLICATIONSCITATIONSRATING
NXNL2 CRISPR Activation Plasmid (h)sc-408554-ACThumanGene ActivationNEWNot Yet Rated
NXNL2 CRISPR Activation Plasmid (m)sc-429023-ACTmouseGene ActivationNEWNot Yet Rated

NXNL siRNA, shRNA Plasmid and shRNA Lentiviral Particles gene silencers include:

PRODUCT NAMECAT. #SPECIESAPPLICATIONSCITATIONSRATING
NXNL2 siRNA (h)sc-92526humanGene SilencingNot Yet Rated
NXNL2 shRNA Plasmid (h)sc-92526-SHhumanGene SilencingNot Yet Rated
NXNL2 shRNA (h) Lentiviral Particlessc-92526-VhumanGene SilencingNot Yet Rated
NXNL2 siRNA (m)sc-150133mouseGene SilencingNot Yet Rated
NXNL2 shRNA Plasmid (m)sc-150133-SHmouseGene SilencingNot Yet Rated
NXNL2 shRNA (m) Lentiviral Particlessc-150133-VmouseGene SilencingNot Yet Rated

NXNL2 (Nucleoredoxin-like protein 2) is a 156 amino acid protein belonging to the Nucleoredoxin family. Other members of the Nucleoredoxin family include Nucleoredoxin (NXN) and NXNL1 (Nucleoredoxin-like protein 1). NXNL2 contains a conserved 139 amino acid thioredoxin (Trx) domain. Thioredoxin serves as a general protein disulphide oxidoreductase. NXNL1 and NXNL2 have been shown to encode rod-derived cone viability factors, RdCVF and RdCVF2, respectively. Expressed in selected regions of the brain as well as the eye, NXNL2 maps to human chromosome 9q22.1 and mouse chromosome 13 A5. Two isoforms exist as a result of alternative splicing events.