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NXNL CRISPR/Cas9 Knockout Plasmids and si/shRNA Gene Silencers

Santa Cruz Biotechnology, Inc. offers a broad range of gene silencers in the form of siRNAs, shRNA Plasmids and shRNA Lentiviral Particles as well as CRISPR/Cas9 Knockout plasmids. NXNL gene silencers are available as NXNL siRNA, NXNL shRNA Plasmid, NXNL shRNA Lentiviral Particles and NXNL CRISPR/Cas9 Knockout plasmids. Gene silencers are useful for gene studies in combination with antibodies used for protein detection.

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PRODUCT NAMECAT. #ISOTYPEEPITOPEAPPLICATIONSSPECIESCITATIONSRATING
NXNL2 (C-17)sc-248125goat IgGInternal (h)WB, IP, IF, ELISAm, r, hNEW
NXNL2 (P-15)sc-248123goat IgGInternal (h)WB, IF, ELISAm, r, hNEW

NXNL CRISPR/Cas9 Knockout Plasmids include:

PRODUCT NAMECAT. #APPLICATIONSSPECIESCITATIONS
NXNL2 CRISPR/Cas9 KO Plasmid (h)sc-408554gene knockouthumanNEW
NXNL2 CRISPR/Cas9 KO Plasmid (m)sc-429023gene knockoutmouseNEW

NXNL siRNA, shRNA Plasmid and shRNA Lentiviral Particles gene silencers include:

siRNAsshRNA PlasmidsshRNA Lentiviral ParticlesCITATIONSRANKING
NXNL2 siRNA (h): sc-92526NXNL2 shRNA Plasmid (h):
sc-92526-SH
NXNL2 shRNA (h)
Lentiviral Particles: sc-92526-V
Not Yet Rated
NXNL2 siRNA (m): sc-150133NXNL2 shRNA Plasmid (m):
sc-150133-SH
NXNL2 shRNA (m)
Lentiviral Particles: sc-150133-V
Not Yet Rated

NXNL2 (Nucleoredoxin-like protein 2) is a 156 amino acid protein belonging to the Nucleoredoxin family. Other members of the Nucleoredoxin family include Nucleoredoxin (NXN) and NXNL1 (Nucleoredoxin-like protein 1). NXNL2 contains a conserved 139 amino acid thioredoxin (Trx) domain. Thioredoxin serves as a general protein disulphide oxidoreductase. NXNL1 and NXNL2 have been shown to encode rod-derived cone viability factors, RdCVF and RdCVF2, respectively. Expressed in selected regions of the brain as well as the eye, NXNL2 maps to human chromosome 9q22.1 and mouse chromosome 13 A5. Two isoforms exist as a result of alternative splicing events.