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NF45 AntibodiesSanta Cruz Biotechnology, Inc. offers a broad range of NF45 antibodies. Select NF45 antibodies from several monoclonal and/or polyclonal NF45 antibodies listed below. View detailed NF45 antibody specifications by linking to the specific product blocks. Select appropriate NF45 antibodies for your research by isotype, epitope, applications and species reactivity. NF45 gene silencer products in siRNA, shRNA Plasmid and shRNA Lentiviral Particle formats are also available. Introducing HOVERcruz™,a unique system for rapid identification of NF45 Antibodies. Hover over product names in the table to see representative data for each product.Live chat is now available! (click here)Our live chat system is available to answer your product and ordering questions.
NF45 siRNA, shRNA Plasmid and shRNA Lentiviral Particles gene silencers include:
NF45 (ILF2, nuclear factor of activated T cells 45 kDa) is a transcription factor that interacts with NF90 (ILF3, DRBP76) to regulate gene expression. NF45 and NF90 are proteins that belong to the double-stranded RNA-binding protein family and both are substrates for the dsRNA-activated protein kinase, PKR. The NF45/NF90 heterodimer is mainly involved in regulating IL-2 expression by binding to the antigen receptor response element (ARRE) target sequence of the IL-2 enhancer. In neuronal cells, the NF45/NF90 heterodimer can repress human rhinovirus type 2 replication by binding to a 5' untranslated region of the viral RNA that encodes the internal ribosome entry site (IRES). |
