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MTHFS Antibodies

Santa Cruz Biotechnology, Inc. offers a broad range of MTHFS antibodies. Select MTHFS antibodies from several monoclonal and/or polyclonal MTHFS antibodies listed below. View detailed MTHFS antibody specifications by linking to the specific product blocks. Select appropriate MTHFS antibodies for your research by isotype, epitope, applications and species reactivity. MTHFS gene silencer products in siRNA, shRNA Plasmid and shRNA Lentiviral Particle formats are also available.

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PRODUCT NAMECAT. #ISOTYPEEPITOPEAPPLICATIONSSPECIESCITATIONSRATING
MTHFS (G-18)sc-66469goat IgGInternal (h)WB, IP, IF, ELISAm, r, h, e, c, b
MTHFS (YZ-M)sc-100563mouse IgG1FL (h)WB, IP, ELISAhuman

MTHFS siRNA, shRNA Plasmid and shRNA Lentiviral Particles gene silencers include:

siRNAsshRNA PlasmidsshRNA Lentiviral ParticlesCITATIONSRANKING
MTHFS siRNA (h): sc-62649MTHFS shRNA Plasmid (h):
sc-62649-SH
MTHFS shRNA (h)
Lentiviral Particles: sc-62649-V
MTHFS siRNA (m): sc-62650MTHFS shRNA Plasmid (m):
sc-62650-SH
MTHFS shRNA (m)
Lentiviral Particles: sc-62650-V

MTHFS (5-formyltetrahydrofolate cyclo-ligase) is a cytosolic protein involved in the formate metabolic process. MTHFS can be account for up to thirty percent of a cells cytoplasmic folate derivitives. MTHFS, with a magnesium cofactor, catalyzes the ATP-dependent reaction that reduces 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate. Folate is a necessary molecule for DNA replication and a deficiency in folate can lead to numerous disease states. During DNA replication 5,10-methenyltetrahydrofolate is oxidized and MTHFS is responsible for resetting the molecule.