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Maspardin AntibodiesSanta Cruz Biotechnology, Inc. offers a broad range of Maspardin antibodies. Select Maspardin antibodies from several monoclonal and/or polyclonal Maspardin antibodies listed below. View detailed Maspardin antibody specifications by linking to the specific product blocks. Select appropriate Maspardin antibodies for your research by isotype, epitope, applications and species reactivity. Maspardin gene silencer products in siRNA, shRNA Plasmid and shRNA Lentiviral Particle formats are also available. Introducing HOVERcruz™,a unique system for rapid identification of Maspardin Antibodies. Hover over product names in the table to see representative data for each product.Live chat is now available! (click here)Our live chat system is available to answer your product and ordering questions.
Maspardin siRNA, shRNA Plasmid and shRNA Lentiviral Particles gene silencers include:
Maspardin, also known as MAST, ACP33, GL010, BM-019 or SPG21 (spastic paraplegia 21 (autosomal recessive, Mast syndrome)), is a 308 amino acid cytoplasmic protein that is widely expressed. Belonging to the AB hydrolase superfamily, Maspardin colocalizes with CD4 on endosomal/trans-Golgi network. It is thought that Maspardin may act as a negative regulatory factor in CD4-dependent T-cell activation. Defects in the gene encoding Maspardin are the result of hereditary spastic paraplegia autosomal recessive type 21 (also designated Mast syndrome), an autosomal recessive neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. The gene encoding Maspardin is encoded by human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome. |
