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LSD1 Antibodies

Santa Cruz Biotechnology, Inc. offers a broad range of LSD1 antibodies. Select LSD1 antibodies from several monoclonal and/or polyclonal LSD1 antibodies listed below. View detailed LSD1 antibody specifications by linking to the specific product blocks. Select appropriate LSD1 antibodies for your research by isotype, epitope, applications and species reactivity. LSD1 gene silencer products in siRNA, shRNA Plasmid, shRNA Lentiviral Particle, CRISPR/Cas9 Knockout and CRISPR Double Nickase Plasmid formats are also available as well as CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems for gene activation.

Introducing HOVERcruz™,

a unique system for rapid identification of LSD1 Antibodies. Hover over the icon next to the product names in the table to see representative data for that product.

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See chemical LSD1 Inhibitors for functional analysis of cellular responses to LSD1.

PRODUCT NAMECAT. #ISOTYPEEPITOPEAPPLICATIONSSPECIESCITATIONSRATING
LSD1 (A-2)
sc-398794mouse IgG2b183-223 (h)WB, IP, IF, ELISAm, r, hNEW
LSD1 (B-9)
sc-271720mouse IgG1581-800 (h)WB, IP, IF, ELISAm, r, h1
LSD1 (H-220)
sc-67272rabbit IgG581-800 (h)WB, IP, IF, IHC(P), ELISAm, r, h, e, c, b, p, a1
LSD1 (1B2E5)
sc-53875mouse IgG1FL (h)WB, IFhuman
LSD1 (P-20)
sc-49294goat IgGN-terminal (h)WB, IF, ELISAm, r, h, e, c, b, p, a
LSD1 (C-19)
sc-49291goat IgGC-terminal (h)WB, IF, ELISAm, r, h, e, c, b, p, a
LSD1 (2D6)
sc-136174mouse IgG289-538 (h)WB, IP, IF, IHC(P)human

LSD1 CRISPR Knockout, HDR and Nickase Knockout Plasmids include:

PRODUCT NAMECAT. #SPECIESAPPLICATIONSMARKERCITATIONS
LSD1 CRISPR/Cas9 KO Plasmid (h)
sc-401294humanGene KnockoutGFPNEW
LSD1 HDR Plasmid (h)
sc-401294-HDRhumanHomology Directed RepairPuromycinNEW
LSD1 Double Nickase Plasmid (h)
sc-401294-NIChumanGene KnockoutPuromycinNEW
LSD1 Double Nickase Plasmid (h2)
sc-401294-NIC-2humanGene KnockoutPuromycinNEW
LSD1 CRISPR/Cas9 KO Plasmid (m)
sc-430289mouseGene KnockoutGFPNEW
LSD1 HDR Plasmid (m)
sc-430289-HDRmouseHomology Directed RepairPuromycinNEW
LSD1 Double Nickase Plasmid (m)
sc-430289-NICmouseGene KnockoutPuromycinNEW
LSD1 Double Nickase Plasmid (m2)
sc-430289-NIC-2mouseGene KnockoutPuromycinNEW

LSD1 CRISPR Activation Plasmids include:

PRODUCT NAMECAT. #SPECIESAPPLICATIONSMARKERCITATIONS
LSD1 CRISPR Activation Plasmid (h)
sc-401294-ACThumanGene ActivationZeo, Blast, HygroNEW
LSD1 CRISPR Activation Plasmid (h2)
sc-401294-ACT-2humanGene ActivationZeo, Blast, HygroNEW
LSD1 Lentiviral Activation Particles (h)
sc-401294-LAChumanGene ActivationZeo, Blast, HygroNEW
LSD1 Lentiviral Activation Particles (h2)
sc-401294-LAC-2humanGene ActivationZeo, Blast, HygroNEW
LSD1 CRISPR Activation Plasmid (m)
sc-430289-ACTmouseGene ActivationZeo, Blast, HygroNEW
LSD1 CRISPR Activation Plasmid (m2)
sc-430289-ACT-2mouseGene ActivationZeo, Blast, HygroNEW
LSD1 Lentiviral Activation Particles (m)
sc-430289-LACmouseGene ActivationZeo, Blast, HygroNEW
LSD1 Lentiviral Activation Particles (m2)
sc-430289-LAC-2mouseGene ActivationZeo, Blast, HygroNEW

LSD1 siRNA, shRNA Plasmid and shRNA Lentiviral Particles gene silencers include:

PRODUCT NAMECAT. #SPECIESAPPLICATIONSMARKERCITATIONS
LSD1 siRNA (h)
sc-60970humanGene SilencingN/A1
LSD1 shRNA Plasmid (h)
sc-60970-SHhumanGene SilencingPuromycin
LSD1 shRNA (h) Lentiviral Particles
sc-60970-VhumanGene SilencingPuromycin
LSD1 siRNA (m)
sc-60971mouseGene SilencingN/A
LSD1 shRNA Plasmid (m)
sc-60971-SHmouseGene SilencingPuromycin
LSD1 shRNA (m) Lentiviral Particles
sc-60971-VmouseGene SilencingPuromycin1
LSD1 siRNA (r)
sc-156072ratGene SilencingN/A
LSD1 shRNA Plasmid (r)
sc-156072-SHratGene SilencingPuromycin
LSD1 shRNA (r) Lentiviral Particles
sc-156072-VratGene SilencingPuromycin
LSD1 siRNA (bovine)
sc-270208bovineGene SilencingN/A
LSD1 shRNA Plasmid (bovine)
sc-270208-SHbovineGene SilencingPuromycin
LSD1 shRNA (bovine) Lentiviral Particles
sc-270208-VbovineGene SilencingPuromycin

Histone methylation regulates chromatin structure and transcription and maintains an epigenetic state of the cell. Histone methylation is dynamically regulated by histone methylases and demethylases. Lysine-specific histone demethylase 1 (LSD1), also designated BHC110, is a flavin-dependent amine oxidase which catalyzes the removal of one or two methyl groups from the methyl-lysine-4 side chain of Histone H3. The LSD1 protein contains a SWIRM domain, a FAD-binding motif and an amine oxidase domain. Association with CoREST, a SANT domain-containing corepressor, positively regulates LSD1. CoREST mediates the demethylation ability of LSD1 and protects it from proteasomal degradation in vivo. PHF21A (also designated BCH80), a PHD domain-containing protein, inhibits activity of LSD1/CoREST mediated de-methylation. The LSD1 protein also co-localizes with the androgen receptor in human prostate tumor cells and in unaffected prostate cells, stimulating androgen-receptor-dependent transcription.