Welcome to Santa Cruz Biotechnology!

LSD1 Antibodies

Santa Cruz Biotechnology, Inc. offers a broad range of LSD1 antibodies. Select LSD1 antibodies from several monoclonal and/or polyclonal LSD1 antibodies listed below. View detailed LSD1 antibody specifications by linking to the specific product blocks. Select appropriate LSD1 antibodies for your research by isotype, epitope, applications and species reactivity. LSD1 gene silencer products in siRNA, shRNA Plasmid, shRNA Lentiviral Particle and CRISPR/Cas9 Knockout Plasmid formats are also available as well as CRISPR/dCas9 Activation Plasmids for gene activation.

Introducing HOVERcruz™,

a unique system for rapid identification of LSD1 Antibodies. Hover over product names in the table to see representative data for each product.

Live chat is now available! (click here)

Our live chat system is available to answer your product and ordering questions.

See chemical LSD1 Inhibitors for functional analysis of cellular responses to LSD1.

PRODUCT NAMECAT. #ISOTYPEEPITOPEAPPLICATIONSSPECIESCITATIONSRATING
LSD1 (A-2)sc-398794mouse IgG2b183-223 (h)WB, IP, IF, ELISAm, r, hNEW
LSD1 (B-9)sc-271720mouse IgG1581-800 (h)WB, IP, IF, ELISAm, r, h1
LSD1 (H-220)sc-67272rabbit IgG581-800 (h)WB, IP, IF, IHC(P), ELISAm, r, h, e, c, b, p, a1
LSD1 (1B2E5)sc-53875mouse IgG1FL (h)WB, IFhuman
LSD1 (P-20)sc-49294goat IgGN-terminal (h)WB, IF, ELISAm, r, h, e, c, b, p, a
LSD1 (C-19)sc-49291goat IgGC-terminal (h)WB, IF, ELISAm, r, h, e, c, b, p, a
LSD1 (2D6)sc-136174mouse IgG289-538 (h)WB, IP, IF, IHC(P)human

LSD1 CRISPR Knockout and HDR Plasmids include:

PRODUCT NAMECAT. #SPECIESAPPLICATIONSCITATIONSRATING
LSD1 CRISPR/Cas9 KO Plasmid (h)sc-401294humanGene KnockoutNEWNot Yet Rated
LSD1 HDR Plasmid (h)sc-401294-HDRhumanHomology Directed RepairNEWNot Yet Rated
LSD1 CRISPR/Cas9 KO Plasmid (m)sc-430289mouseGene KnockoutNEWNot Yet Rated
LSD1 HDR Plasmid (m)sc-430289-HDRmouseHomology Directed RepairNEWNot Yet Rated

LSD1 CRISPR Activation Plasmids include:

PRODUCT NAMECAT. #SPECIESAPPLICATIONSCITATIONSRATING
LSD1 CRISPR Activation Plasmid (h)sc-401294-ACThumanGene ActivationNEWNot Yet Rated
LSD1 CRISPR Activation Plasmid (m)sc-430289-ACTmouseGene ActivationNEWNot Yet Rated

LSD1 siRNA, shRNA Plasmid and shRNA Lentiviral Particles gene silencers include:

PRODUCT NAMECAT. #SPECIESAPPLICATIONSCITATIONSRATING
LSD1 siRNA (h)sc-60970humanGene Silencing1
LSD1 shRNA Plasmid (h)sc-60970-SHhumanGene Silencing
LSD1 shRNA (h) Lentiviral Particlessc-60970-VhumanGene Silencing
LSD1 siRNA (m)sc-60971mouseGene Silencing
LSD1 shRNA Plasmid (m)sc-60971-SHmouseGene Silencing
LSD1 shRNA (m) Lentiviral Particlessc-60971-VmouseGene Silencing1
LSD1 siRNA (r)sc-156072ratGene Silencing
LSD1 shRNA Plasmid (r)sc-156072-SHratGene Silencing
LSD1 shRNA (r) Lentiviral Particlessc-156072-VratGene Silencing
LSD1 siRNA (bovine)sc-270208bovineGene Silencing
LSD1 shRNA Plasmid (bovine)sc-270208-SHbovineGene Silencing
LSD1 shRNA (bovine) Lentiviral Particlessc-270208-VbovineGene Silencing

Histone methylation regulates chromatin structure and transcription and maintains an epigenetic state of the cell. Histone methylation is dynamically regulated by histone methylases and demethylases. Lysine-specific histone demethylase 1 (LSD1), also designated BHC110, is a flavin-dependent amine oxidase which catalyzes the removal of one or two methyl groups from the methyl-lysine-4 side chain of Histone H3. The LSD1 protein contains a SWIRM domain, a FAD-binding motif and an amine oxidase domain. Association with CoREST, a SANT domain-containing corepressor, positively regulates LSD1. CoREST mediates the demethylation ability of LSD1 and protects it from proteasomal degradation in vivo. PHF21A (also designated BCH80), a PHD domain-containing protein, inhibits activity of LSD1/CoREST mediated de-methylation. The LSD1 protein also co-localizes with the androgen receptor in human prostate tumor cells and in unaffected prostate cells, stimulating androgen-receptor-dependent transcription.