Jun Antibodies

Santa Cruz Biotechnology, Inc. offers a broad range of Jun antibodies. Select Jun antibodies from several monoclonal and/or polyclonal Jun antibodies listed below. View detailed Jun antibody specifications by linking to the specific product blocks. Select appropriate Jun antibodies for your research by isotype, epitope, applications and species reactivity. Jun gene silencer products in siRNA, shRNA Plasmid and shRNA Lentiviral Particle formats are also available.

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See Jun Activators for functional analysis of cellular responses to Jun.

Also see additional Jun Antibodies including, c-Jun, Jun B, Jun D

The c-Jun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus v-Jun oncogene. The c-Jun protein, along with c-Fos, is a component of the AP-1 transcriptional complex. c-Jun can form either Jun/Jun homodimers or Jun/Fos heterodimers via the leucine repeats in both proteins. Homo- and heterodimers bind to the TGACTCA consensus sequence present in numerous promoters and initially identified as the phorbol ester tumor promoter response element (TRE). Two additional genes, Jun B and Jun D, have been shown to be almost identical to c-Jun in their C-terminal regions, which are involved in dimerization and DNA binding, whereas their N-terminal domains, which are involved in transcriptional activation, diverge. All three form heterodimers among themselves and with c-Fos and other members of the Fos gene family.