Jagged Antibodies

Santa Cruz Biotechnology, Inc. offers a broad range of Jagged antibodies. Select Jagged antibodies from several monoclonal and/or polyclonal Jagged antibodies listed below. View detailed Jagged antibody specifications by linking to the specific product blocks. Select appropriate Jagged antibodies for your research by isotype, epitope, applications and species reactivity. Jagged gene silencer products in siRNA, shRNA Plasmid and shRNA Lentiviral Particle formats are also available.

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Also see additional Jagged Antibodies including, Jagged1, Jagged2

PRODUCT NAME	CAT. #	ISOTYPE	EPITOPE	APPLICATIONS	SPECIES	CITATIONS
Jagged1 (E-12)	sc-390177	mouse IgG₁	1110-1223 (h)	WB, IP, IF, ELISA	h, e
Jagged1 (C-20)	sc-6011	goat IgG	C-terminus (r)	WB, IP, IF, IHC(P), ELISA	m, r, h, c, b, p, a	70
Jagged1 (H-66)	sc-11376	rabbit IgG	207-272 (h)	WB, IP, IF, IHC(P), ELISA	m, r, h, c, b, p, e	8
Jagged1 (N-17)	sc-34473	goat IgG	N-terminus (h)	WB, IP, IF, IHC(P), ELISA	m, r, h, c, b, p
Jagged1 (T-19)	sc-34474	goat IgG	internal (h)	WB, IP, IF, IHC(P), ELISA	m, r, h, e, c, b, p, a
Jagged1 (H-114)	sc-8303	rabbit IgG	1110-1223 (h)	WB, IP, IF, IHC(P), ELISA	m, r, h, c, b, p, a, e	48
Jagged1 (21)	sc-135955	mouse IgG₁	N/A	WB, IP	m, r, h
Jagged2 (H-143)	sc-5604	rabbit IgG	914-1056 (h)	WB, IP, IF, IHC(P), ELISA	m, r, h	13
Jagged2 (C-17)	sc-8157	goat IgG	C-terminus (h)	WB, IF, ELISA	human	8
Jagged2 (N-19)	sc-34475	goat IgG	N-terminus (h)	WB, IP, IF, ELISA	m, r, h, p, c, p
Jagged2 (R-19)	sc-8158	goat IgG	C-terminus (r)	WB, IF, ELISA	m, r	8
Jagged2 (S-16)	sc-34476	goat IgG	C-terminus (h)	WB, IP, IF, ELISA	m, r, h, c, b, p	1

Jagged siRNA, shRNA Plasmid and shRNA Lentiviral Particles gene silencers include:

siRNAs	shRNA Plasmids	shRNA Lentiviral Particles	CITATIONS
Jagged1 siRNA (h): sc-37202	Jagged1 shRNA Plasmid (h): sc-37202-SH	Jagged1 shRNA (h) Lentiviral Particles: sc-37202-V	3
Jagged1 siRNA (m): sc-37203	Jagged1 shRNA Plasmid (m): sc-37203-SH	Jagged1 shRNA (m) Lentiviral Particles: sc-37203-V
Jagged1 siRNA (h2): sc-44335	Jagged1 shRNA Plasmid (h2): sc-44335-SH	Jagged1 shRNA (h2) Lentiviral Particles: sc-44335-V	2
Jagged1 siRNA (m2): sc-44336	Jagged1 shRNA Plasmid (m2): sc-44336-SH	Jagged1 shRNA (m2) Lentiviral Particles: sc-44336-V
Jagged1 siRNA (r): sc-61881	Jagged1 shRNA Plasmid (r): sc-61881-SH	Jagged1 shRNA (r) Lentiviral Particles: sc-61881-V	1
Jagged2 siRNA (h): sc-39672	Jagged2 shRNA Plasmid (h): sc-39672-SH	Jagged2 shRNA (h) Lentiviral Particles: sc-39672-V
Jagged2 siRNA (m): sc-39673	Jagged2 shRNA Plasmid (m): sc-39673-SH	Jagged2 shRNA (m) Lentiviral Particles: sc-39673-V

The LIN-12/Notch family of transmembrane receptors is believed to play a central role in development by regulating cell fate decisions. Ligands for Notch include Jagged1, Jagged2 and Delta. Jagged is a membrane protein and can activate Notch and prevent myoblast differentiation by inhibiting the expression of muscle regulatory and structural genes. It is involved in mammalian cardiovascular development and in cell-fate decisions during hematopoiesis. Jagged is expressed in adult and fetal tissues, and expression is upregulated in cervical squamous cell carcinoma. Familial Tetralogy of Fallot, the most common form of complex congenital heart disease, is caused by a mutation in the Jagged1 gene.