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IF Antibodies

Santa Cruz Biotechnology, Inc. offers a broad range of IF antibodies. Select IF antibodies from several monoclonal and/or polyclonal IF antibodies listed below. View detailed IF antibody specifications by linking to the specific product blocks. Select appropriate IF antibodies for your research by isotype, epitope, applications and species reactivity. IF gene silencer products in siRNA, shRNA Plasmid and shRNA Lentiviral Particle formats are also available.

Introducing HOVERcruz™,

a unique system for rapid identification of IF Antibodies. Hover over product names in the table to see representative data for each product.

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Also see additional IF Antibodies including, IF2, IF3, Mtif3

PRODUCT NAMECAT. #ISOTYPEEPITOPEAPPLICATIONSSPECIESCITATIONSRATING
IF2 (H-5)sc-365477mouse IgG2a428-727 (h)WB, IP, IF, ELISAhuman
IF2 (H-300)sc-98288rabbit IgG428-727 (h)WB, IP, IF, ELISAm, r, h, e, p
IF2 (S-15)sc-107621goat IgGInternal (h)WB, IF, ELISAm, r, h, e, c, b, p
IF3 (G-20)sc-84313rabbit IgGInternal (h)WB, IF, ELISAh, e, b, p
IF3 (T-20)sc-84315rabbit IgGInternal (h)WB, IF, ELISAhuman

IF siRNA, shRNA Plasmid and shRNA Lentiviral Particles gene silencers include:

siRNAsshRNA PlasmidsshRNA Lentiviral ParticlesCITATIONSRANKING
IF2 siRNA (h): sc-94300IF2 shRNA Plasmid (h):
sc-94300-SH
IF2 shRNA (h)
Lentiviral Particles: sc-94300-V
IF2 siRNA (m): sc-146149IF2 shRNA Plasmid (m):
sc-146149-SH
IF2 shRNA (m)
Lentiviral Particles: sc-146149-V
IF3 siRNA (h): sc-75319IF3 shRNA Plasmid (h):
sc-75319-SH
IF3 shRNA (h)
Lentiviral Particles: sc-75319-V
Mtif3 siRNA (m): sc-149682Mtif3 shRNA Plasmid (m):
sc-149682-SH
Mtif3 shRNA (m)
Lentiviral Particles: sc-149682-V

The initiation of protein synthesis in eukaryotic cells is regulated by interactions between protein initiation factors and RNA molecules. IF2, also known as MTIF2 (mitochondrial translational initiation factor 2), is a 727 amino acid protein that localizes to mitochondria and is expressed ubiquitously, with highest expression in skeletal muscle. Functioning as a monomer, IF2 exists as an essential component of protein synthesis, specifically promoting the GTP-dependent binding of initiator tRNA to the ribosome and possibly playing a role in the formation of the 70S ribosomal complex. IF3 is also known as MTIF3 (mitochondrial translational initiation factor 3), DC38, IF3(mt) or IF-3mt, and is a 278 amino acid protein that is localized to mitochondria. IF3 aids in the initiation of protein synthesis by binding the 28S ribosomal subunit, which is a protein synthesis initiation site. The 28S and 39S ribosomal structures are subunits of the 55S ribosome, whose formation is favored in the absence of IF3, because IF3 allows the subunits to remain in their free form.