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HTR3 Antibodies

Santa Cruz Biotechnology, Inc. offers a broad range of HTR3 antibodies. Select HTR3 antibodies from several monoclonal and/or polyclonal HTR3 antibodies listed below. View detailed HTR3 antibody specifications by linking to the specific product blocks. Select appropriate HTR3 antibodies for your research by isotype, epitope, applications and species reactivity. HTR3 gene silencer products in siRNA, shRNA Plasmid and shRNA Lentiviral Particle formats are also available.

Introducing HOVERcruz™,

a unique system for rapid identification of HTR3 Antibodies. Hover over product names in the table to see representative data for each product.

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Our live chat system is available to answer your product and ordering questions.

See HTR3 Activators for functional analysis of cellular responses to HTR3.

Also see additional HTR3 Antibodies including, HTR3C, HTR3D, HTR3E

HTR3C (T-14)sc-102601goat IgGInternal (h)WB, IP, IF, ELISAh, cNEW
HTR3D (C-15)sc-102603rabbit IgGC-terminal (h)WB, IP, IF, ELISAhuman
HTR3D (K-13)sc-102604rabbit IgGCytoplasmic (h)WB, IP, IF, ELISAhuman
HTR3E (S-12)sc-102608goat IgGInternal (h)WB, IF, ELISAh, c, b
HTR3E (T-13)sc-102609goat IgGInternal (h)WB, IF, ELISAhuman

HTR3 siRNA, shRNA Plasmid and shRNA Lentiviral Particles gene silencers include:

siRNAsshRNA PlasmidsshRNA Lentiviral ParticlesCITATIONSRANKING
HTR3C siRNA (h): sc-78193HTR3C shRNA Plasmid (h):
HTR3C shRNA (h)
Lentiviral Particles: sc-78193-V
HTR3D siRNA (h): sc-78056HTR3D shRNA Plasmid (h):
HTR3D shRNA (h)
Lentiviral Particles: sc-78056-V
HTR3E siRNA (h): sc-78474HTR3E shRNA Plasmid (h):
HTR3E shRNA (h)
Lentiviral Particles: sc-78474-V

The SR (Serotonin (5-hydroxytryptamine, or 5-HT) receptor) is a 5 subunit, oligomeric complex and HTR3E (5-hydroxytryptamine receptor 3, family member E) is a subunit of the SR. HTR3E is also known as 5-HT3E or SR 3E and is a 456 amino acid protein that is expressed in adult colon and intestinal tissues. HTR3E, which is expressed as five isoforms, contains four transmembrane spanning domains and is localized to the cellular membrane where it exists as a multi-pass membrane protein and belongs to the ligand-gated ionic channel family. HTR3E is thought to be closely related to HTR3C and HTR3D, which also function as subunits of SRs. The genes encoding these 3 subunits map very close to each other on chromosome 3. HTR3E, HTR3C and HTR3D are thought to be expressed individually within the endoplasmic reticulum (ER) and are detected elsewhere when coexpressed with HTR3A. HTR3E forms a pentaheteromeric complex with HTR3A, the result of which is a ligand-gated ionic SR which functions as a neurotransmitter, a hormone and a mitogen. This receptor is specific for cations and, when activated, causes fast depolarization in neurons. Due to its expression in colon and intestine, HTR3E may be involved in Serotonin functions within the gut, possibly functioning as a target for treatment of irritable bowel syndrome (IBS).