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HTR3 Antibodies

Santa Cruz Biotechnology, Inc. offers a broad range of HTR3 antibodies. Select HTR3 antibodies from several monoclonal and/or polyclonal HTR3 antibodies listed below. View detailed HTR3 antibody specifications by linking to the specific product blocks. Select appropriate HTR3 antibodies for your research by isotype, epitope, applications and species reactivity. HTR3 gene silencer products in siRNA, shRNA Plasmid, shRNA Lentiviral Particle, CRISPR/Cas9 Knockout and CRISPR Double Nickase Plasmid formats are also available as well as CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems for gene activation.

Introducing HOVERcruz™,

a unique system for rapid identification of HTR3 Antibodies. Hover over the icon next to the product names in the table to see representative data for that product.

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Our live chat system is available to answer your product and ordering questions.

See chemical HTR3 Inhibitors or chemical HTR3 Activators for functional analysis of cellular responses to HTR3.

Also see additional HTR3 Antibodies including, HTR3C, HTR3D, HTR3E

HTR3D (G-5)
sc-515279mouse IgG1378-396 (h)WB, IP, IF, ELISAhumanNEW
HTR3D (C-15)
sc-102603rabbit IgGC-terminal (h)WB, IP, IF, ELISAhuman
HTR3D (K-13)
sc-102604rabbit IgGCytoplasmic (h)WB, IP, IF, ELISAhuman

HTR3 CRISPR Knockout, HDR and Nickase Knockout Plasmids include:

HTR3C CRISPR/Cas9 KO Plasmid (h)
sc-414932humanGene KnockoutGFPNEW
HTR3C HDR Plasmid (h)
sc-414932-HDRhumanHomology Directed RepairPuromycinNEW
HTR3C Double Nickase Plasmid (h)
sc-414932-NIChumanGene KnockoutPuromycinNEW
HTR3C Double Nickase Plasmid (h2)
sc-414932-NIC-2humanGene KnockoutPuromycinNEW
HTR3D CRISPR/Cas9 KO Plasmid (h)
sc-415002humanGene KnockoutGFPNEW
HTR3D HDR Plasmid (h)
sc-415002-HDRhumanHomology Directed RepairPuromycinNEW
HTR3D Double Nickase Plasmid (h)
sc-415002-NIChumanGene KnockoutPuromycinNEW
HTR3D Double Nickase Plasmid (h2)
sc-415002-NIC-2humanGene KnockoutPuromycinNEW
HTR3E CRISPR/Cas9 KO Plasmid (h)
sc-418317humanGene KnockoutGFPNEW
HTR3E HDR Plasmid (h)
sc-418317-HDRhumanHomology Directed RepairPuromycinNEW
HTR3E Double Nickase Plasmid (h)
sc-418317-NIChumanGene KnockoutPuromycinNEW
HTR3E Double Nickase Plasmid (h2)
sc-418317-NIC-2humanGene KnockoutPuromycinNEW

HTR3 CRISPR Activation Plasmids include:

HTR3C CRISPR Activation Plasmid (h)
sc-414932-ACThumanGene ActivationPuro, Blast, HygroNEW
HTR3C CRISPR Activation Plasmid (h2)
sc-414932-ACT-2humanGene ActivationPuro, Blast, HygroNEW
HTR3C Lentiviral Activation Particles (h)
sc-414932-LAChumanGene ActivationPuro, Blast, HygroNEW
HTR3C Lentiviral Activation Particles (h2)
sc-414932-LAC-2humanGene ActivationPuro, Blast, HygroNEW
HTR3D CRISPR Activation Plasmid (h)
sc-415002-ACThumanGene ActivationPuro, Blast, HygroNEW
HTR3D CRISPR Activation Plasmid (h2)
sc-415002-ACT-2humanGene ActivationPuro, Blast, HygroNEW
HTR3D Lentiviral Activation Particles (h)
sc-415002-LAChumanGene ActivationPuro, Blast, HygroNEW
HTR3D Lentiviral Activation Particles (h2)
sc-415002-LAC-2humanGene ActivationPuro, Blast, HygroNEW
HTR3E CRISPR Activation Plasmid (h)
sc-418317-ACThumanGene ActivationPuro, Blast, HygroNEW
HTR3E CRISPR Activation Plasmid (h2)
sc-418317-ACT-2humanGene ActivationPuro, Blast, HygroNEW
HTR3E Lentiviral Activation Particles (h)
sc-418317-LAChumanGene ActivationPuro, Blast, HygroNEW
HTR3E Lentiviral Activation Particles (h2)
sc-418317-LAC-2humanGene ActivationPuro, Blast, HygroNEW

HTR3 siRNA, shRNA Plasmid and shRNA Lentiviral Particles gene silencers include:

HTR3D siRNA (h)
sc-78056humanGene SilencingN/A
HTR3D shRNA Plasmid (h)
sc-78056-SHhumanGene SilencingPuromycin
HTR3D shRNA (h) Lentiviral Particles
sc-78056-VhumanGene SilencingPuromycin
HTR3C siRNA (h)
sc-78193humanGene SilencingN/A
HTR3C shRNA Plasmid (h)
sc-78193-SHhumanGene SilencingPuromycin
HTR3C shRNA (h) Lentiviral Particles
sc-78193-VhumanGene SilencingPuromycin
HTR3E siRNA (h)
sc-78474humanGene SilencingN/A
HTR3E shRNA Plasmid (h)
sc-78474-SHhumanGene SilencingPuromycin
HTR3E shRNA (h) Lentiviral Particles
sc-78474-VhumanGene SilencingPuromycin

The SR (Serotonin (5-hydroxytryptamine, or 5-HT) receptor) is a 5 subunit, oligomeric complex and HTR3E (5-hydroxytryptamine receptor 3, family member E) is a subunit of the SR. HTR3E is also known as 5-HT3E or SR 3E and is a 456 amino acid protein that is expressed in adult colon and intestinal tissues. HTR3E, which is expressed as five isoforms, contains four transmembrane spanning domains and is localized to the cellular membrane where it exists as a multi-pass membrane protein and belongs to the ligand-gated ionic channel family. HTR3E is thought to be closely related to HTR3C and HTR3D, which also function as subunits of SRs. The genes encoding these 3 subunits map very close to each other on chromosome 3. HTR3E, HTR3C and HTR3D are thought to be expressed individually within the endoplasmic reticulum (ER) and are detected elsewhere when coexpressed with HTR3A. HTR3E forms a pentaheteromeric complex with HTR3A, the result of which is a ligand-gated ionic SR which functions as a neurotransmitter, a hormone and a mitogen. This receptor is specific for cations and, when activated, causes fast depolarization in neurons. Due to its expression in colon and intestine, HTR3E may be involved in Serotonin functions within the gut, possibly functioning as a target for treatment of irritable bowel syndrome (IBS).