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HESX Antibodies

Santa Cruz Biotechnology, Inc. offers a broad range of HESX antibodies. Select HESX antibodies from several monoclonal and/or polyclonal HESX antibodies listed below. View detailed HESX antibody specifications by linking to the specific product blocks. Select appropriate HESX antibodies for your research by isotype, epitope, applications and species reactivity. HESX gene silencer products in siRNA, shRNA Plasmid, shRNA Lentiviral Particle and CRISPR/Cas9 Knockout Plasmid formats are also available.

Introducing HOVERcruz™,

a unique system for rapid identification of HESX Antibodies. Hover over product names in the table to see representative data for each product.

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HESX1 (L-19)sc-15122goat IgGinternal (h)WB, IF, ELISAhuman
HESX1 (M-20)sc-15126goat IgGinternal (m)WB, IF, ELISAm, r
HESX1 (N-17)sc-15121goat IgGN-terminal (h)WB, IF, ELISAh, c
HESX1 (P-17)sc-15125goat IgGN-terminal (m)WB, IF, ELISAm, r

HESX CRISPR/Cas9 Knockout Plasmids include:

HESX1 CRISPR/Cas9 KO Plasmid (h)sc-409466gene knockouthumanNEW
HESX1 CRISPR/Cas9 KO Plasmid (m)sc-420836gene knockoutmouseNEW

HESX siRNA, shRNA Plasmid and shRNA Lentiviral Particles gene silencers include:

siRNAsshRNA PlasmidsshRNA Lentiviral ParticlesCITATIONSRANKING
HESX1 siRNA (h): sc-38669HESX1 shRNA Plasmid (h):
HESX1 shRNA (h)
Lentiviral Particles: sc-38669-V
Not Yet Rated
HESX1 siRNA (m): sc-38670HESX1 shRNA Plasmid (m):
HESX1 shRNA (m)
Lentiviral Particles: sc-38670-V
Not Yet Rated

The homeobox protein, HESX1, which is also known as Rathke’s pouch homeobox, HANF, homeodomain transcription factor, and anterior-restricted homeobox protein is a transcription factor that belongs to the homeodomain family of DNA binding proteins. HESX1 is initially expressed in embryonic stem cells and the primitive forebrain, and is essential for normal development of the eyes and other anterior CNS structures, such as the hypothalamus, the pituitary gland and the olfactory bulbs. The homeobox gene Hesx1 is expressed in the anterior visceral endoderm (AVE), anterior axial mesendoderm (AME), and anterior neural ectoderm (ANE) during early embryogenesis. Mutations in the Hesx1 gene are associated with disorders that are comparable with septo-optic dysplasia (SOD). These disorders are characterized by hypoplasia of the optic nerve, various types of forebrain defects and pituitary hormone deficiencies, including hypothyroidism. Hesx1 also acts as a transcriptional repressor of reporter gene constructs in tissue culture assays.