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HESX Antibodies

Santa Cruz Biotechnology, Inc. offers a broad range of HESX antibodies. Select HESX antibodies from several monoclonal and/or polyclonal HESX antibodies listed below. View detailed HESX antibody specifications by linking to the specific product blocks. Select appropriate HESX antibodies for your research by isotype, epitope, applications and species reactivity. HESX gene silencer products in siRNA, shRNA Plasmid, shRNA Lentiviral Particle, CRISPR/Cas9 Knockout and CRISPR Double Nickase Plasmid formats are also available as well as CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems for gene activation.

Introducing HOVERcruz™,

a unique system for rapid identification of HESX Antibodies. Hover over the icon next to the product names in the table to see representative data for that product.

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PRODUCT NAMECAT. #ISOTYPEEPITOPEAPPLICATIONSSPECIESCITATIONSRATING
HESX1 (L-19)
sc-15122goat IgGinternal (h)WB, IF, ELISAhuman
HESX1 (M-20)
sc-15126goat IgGinternal (m)WB, IF, ELISAm, r
HESX1 (N-17)
sc-15121goat IgGN-terminal (h)WB, IF, ELISAh, c
HESX1 (P-17)
sc-15125goat IgGN-terminal (m)WB, IF, ELISAm, r

HESX CRISPR Knockout, HDR and Nickase Knockout Plasmids include:

PRODUCT NAMECAT. #SPECIESAPPLICATIONSMARKERCITATIONS
HESX1 CRISPR/Cas9 KO Plasmid (h)
sc-409466humanGene KnockoutGFPNEW
HESX1 HDR Plasmid (h)
sc-409466-HDRhumanHomology Directed RepairPuromycinNEW
HESX1 Double Nickase Plasmid (h)
sc-409466-NIChumanGene KnockoutPuromycinNEW
HESX1 Double Nickase Plasmid (h2)
sc-409466-NIC-2humanGene KnockoutPuromycinNEW
HESX1 CRISPR/Cas9 KO Plasmid (m)
sc-420836mouseGene KnockoutGFPNEW
HESX1 HDR Plasmid (m)
sc-420836-HDRmouseHomology Directed RepairPuromycinNEW
HESX1 Double Nickase Plasmid (m)
sc-420836-NICmouseGene KnockoutPuromycinNEW
HESX1 Double Nickase Plasmid (m2)
sc-420836-NIC-2mouseGene KnockoutPuromycinNEW

HESX CRISPR Activation Plasmids include:

PRODUCT NAMECAT. #SPECIESAPPLICATIONSMARKERCITATIONS
HESX1 CRISPR Activation Plasmid (h)
sc-409466-ACThumanGene ActivationZeo, Blast, HygroNEW
HESX1 CRISPR Activation Plasmid (h2)
sc-409466-ACT-2humanGene ActivationZeo, Blast, HygroNEW
HESX1 Lentiviral Activation Particles (h)
sc-409466-LAChumanGene ActivationZeo, Blast, HygroNEW
HESX1 Lentiviral Activation Particles (h2)
sc-409466-LAC-2humanGene ActivationZeo, Blast, HygroNEW
HESX1 CRISPR Activation Plasmid (m)
sc-420836-ACTmouseGene ActivationZeo, Blast, HygroNEW
HESX1 CRISPR Activation Plasmid (m2)
sc-420836-ACT-2mouseGene ActivationZeo, Blast, HygroNEW
HESX1 Lentiviral Activation Particles (m)
sc-420836-LACmouseGene ActivationZeo, Blast, HygroNEW
HESX1 Lentiviral Activation Particles (m2)
sc-420836-LAC-2mouseGene ActivationZeo, Blast, HygroNEW

HESX siRNA, shRNA Plasmid and shRNA Lentiviral Particles gene silencers include:

PRODUCT NAMECAT. #SPECIESAPPLICATIONSMARKERCITATIONS
HESX1 siRNA (h)
sc-38669humanGene SilencingN/A
HESX1 shRNA Plasmid (h)
sc-38669-SHhumanGene SilencingPuromycin
HESX1 shRNA (h) Lentiviral Particles
sc-38669-VhumanGene SilencingPuromycin
HESX1 siRNA (m)
sc-38670mouseGene SilencingN/A
HESX1 shRNA Plasmid (m)
sc-38670-SHmouseGene SilencingPuromycin
HESX1 shRNA (m) Lentiviral Particles
sc-38670-VmouseGene SilencingPuromycin

The homeobox protein, HESX1, which is also known as Rathke’s pouch homeobox, HANF, homeodomain transcription factor, and anterior-restricted homeobox protein is a transcription factor that belongs to the homeodomain family of DNA binding proteins. HESX1 is initially expressed in embryonic stem cells and the primitive forebrain, and is essential for normal development of the eyes and other anterior CNS structures, such as the hypothalamus, the pituitary gland and the olfactory bulbs. The homeobox gene Hesx1 is expressed in the anterior visceral endoderm (AVE), anterior axial mesendoderm (AME), and anterior neural ectoderm (ANE) during early embryogenesis. Mutations in the Hesx1 gene are associated with disorders that are comparable with septo-optic dysplasia (SOD). These disorders are characterized by hypoplasia of the optic nerve, various types of forebrain defects and pituitary hormone deficiencies, including hypothyroidism. Hesx1 also acts as a transcriptional repressor of reporter gene constructs in tissue culture assays.