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HESX Antibodies

Santa Cruz Biotechnology, Inc. offers a broad range of HESX antibodies. Select HESX antibodies from several monoclonal and/or polyclonal HESX antibodies listed below. View detailed HESX antibody specifications by linking to the specific product blocks. Select appropriate HESX antibodies for your research by isotype, epitope, applications and species reactivity. HESX gene silencer products in siRNA, shRNA Plasmid, shRNA Lentiviral Particle and CRISPR/Cas9 Knockout Plasmid formats are also available as well as CRISPR/dCas9 Activation Plasmids for gene activation.

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a unique system for rapid identification of HESX Antibodies. Hover over product names in the table to see representative data for each product.

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PRODUCT NAMECAT. #ISOTYPEEPITOPEAPPLICATIONSSPECIESCITATIONSRATING
HESX1 (L-19)sc-15122goat IgGinternal (h)WB, IF, ELISAhuman
HESX1 (M-20)sc-15126goat IgGinternal (m)WB, IF, ELISAm, r
HESX1 (N-17)sc-15121goat IgGN-terminal (h)WB, IF, ELISAh, c
HESX1 (P-17)sc-15125goat IgGN-terminal (m)WB, IF, ELISAm, r

HESX CRISPR Knockout and HDR Plasmids include:

PRODUCT NAMECAT. #SPECIESAPPLICATIONSCITATIONSRATING
HESX1 CRISPR/Cas9 KO Plasmid (h)sc-409466humanGene KnockoutNEWNot Yet Rated
HESX1 HDR Plasmid (h)sc-409466-HDRhumanHomology Directed RepairNEWNot Yet Rated
HESX1 CRISPR/Cas9 KO Plasmid (m)sc-420836mouseGene KnockoutNEWNot Yet Rated
HESX1 HDR Plasmid (m)sc-420836-HDRmouseHomology Directed RepairNEWNot Yet Rated

HESX CRISPR Activation Plasmids include:

PRODUCT NAMECAT. #SPECIESAPPLICATIONSCITATIONSRATING
HESX1 CRISPR Activation Plasmid (h)sc-409466-ACThumanGene ActivationNEWNot Yet Rated
HESX1 CRISPR Activation Plasmid (m)sc-420836-ACTmouseGene ActivationNEWNot Yet Rated

HESX siRNA, shRNA Plasmid and shRNA Lentiviral Particles gene silencers include:

PRODUCT NAMECAT. #SPECIESAPPLICATIONSCITATIONSRATING
HESX1 siRNA (h)sc-38669humanGene SilencingNot Yet Rated
HESX1 shRNA Plasmid (h)sc-38669-SHhumanGene SilencingNot Yet Rated
HESX1 shRNA (h) Lentiviral Particlessc-38669-VhumanGene SilencingNot Yet Rated
HESX1 siRNA (m)sc-38670mouseGene SilencingNot Yet Rated
HESX1 shRNA Plasmid (m)sc-38670-SHmouseGene SilencingNot Yet Rated
HESX1 shRNA (m) Lentiviral Particlessc-38670-VmouseGene SilencingNot Yet Rated

The homeobox protein, HESX1, which is also known as Rathke’s pouch homeobox, HANF, homeodomain transcription factor, and anterior-restricted homeobox protein is a transcription factor that belongs to the homeodomain family of DNA binding proteins. HESX1 is initially expressed in embryonic stem cells and the primitive forebrain, and is essential for normal development of the eyes and other anterior CNS structures, such as the hypothalamus, the pituitary gland and the olfactory bulbs. The homeobox gene Hesx1 is expressed in the anterior visceral endoderm (AVE), anterior axial mesendoderm (AME), and anterior neural ectoderm (ANE) during early embryogenesis. Mutations in the Hesx1 gene are associated with disorders that are comparable with septo-optic dysplasia (SOD). These disorders are characterized by hypoplasia of the optic nerve, various types of forebrain defects and pituitary hormone deficiencies, including hypothyroidism. Hesx1 also acts as a transcriptional repressor of reporter gene constructs in tissue culture assays.