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HDAC Antibodies

Santa Cruz Biotechnology, Inc. offers a broad range of HDAC antibodies. Select HDAC antibodies from several monoclonal and/or polyclonal HDAC antibodies listed below. View detailed HDAC antibody specifications by linking to the specific product blocks. Select appropriate HDAC antibodies for your research by isotype, epitope, applications and species reactivity. HDAC gene silencer products in siRNA, shRNA Plasmid, shRNA Lentiviral Particle and CRISPR/Cas9 Knockout Plasmid formats are also available.

Introducing HOVERcruz™,

a unique system for rapid identification of HDAC Antibodies. Hover over product names in the table to see representative data for each product.

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See chemical HDAC Inhibitors, chemical HDAC Activators or chemical HDAC Substrates for functional analysis of cellular responses to HDAC.

Also see additional HDAC Antibodies including, HDAC1, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7... See More, HDAC8, HDAC9, HDAC10, HDAC11

HDAC1 (10E2)sc-81598mouse IgG1467-482 (h)WB, IP, IF, IHC(P)m, r, h6
HDAC1 (C-19)sc-6298goat IgGC-terminal (h)WB, IP, IF, IHC(P), ELISAm, r, h64
HDAC1 (H-11)sc-8410mouse IgG1432-482 (h)WB, IP, IF, FCM, ELISAm, r, h56
HDAC1 (H-51)sc-7872rabbit IgG432-482 (h)WB, IP, IF, IHC(P), ELISAm, r, h, c, b, p, e147
HDAC1 (N-19)sc-6299goat IgGN-terminal (h)WB, IP, IF, IHC(P), ELISAm, r, h, zebrafish, Xenopus, c, b, a11
HDAC2 (3F3)sc-81599mouse IgG1473-488 (h)WB, IP, IFm, r, h, b5
HDAC2 (B-2)sc-55541mouse IgG1435-488 (h)WB, IP, IF, ELISAm, h2
HDAC2 (C-19)sc-6296goat IgGC-terminal (h)WB, IP, IF, IHC(P), FCM, ELISAm, r, h, e, b, p, c, a33
HDAC2 (C-8)sc-9959mouse IgG435-488 (h)WB, IP, IF, IHC(P)m, h32
HDAC2 (F-6)sc-55542mouse IgG1435-488 (h)WB, IP, IF, ELISAm, h1
HDAC2 (H-54)sc-7899rabbit IgG435-488 (h)WB, IP, IF, IHC(P), ELISAm, r, h, c, b, p, a, e104
HDAC2 (HDAC2-62)sc-56685mouse IgG2b471-488 (h)WB, IP, IFm, r, h
HDAC3 (A-3)sc-376957mouse IgG12-29 (h)WB, IP, IF, ELISAh, e, c, b, p, a
HDAC3 (3G6)sc-81600mouse IgG2a411-428 (h)WB, IP, IF, IHC(P)m, h1
HDAC3 (1)sc-130319mouse IgG1FL (h)WB, ELISAhuman1
HDAC3 (B-12)sc-17795mouse IgG2a330-428 (h)WB, IP, IF, ELISAm, r, h, e, c, b, p13
HDAC3 (H-99)sc-11417rabbit IgG330-428 (h)WB, IP, IF, IHC(P), ELISAm, r, h, e, c, b, p, a85
HDAC3 (N-19)sc-8138goat IgGN-terminal (h)WB, IP, IF, ELISAh, e, c, b, p, a, Drosophila23
HDAC3 (40)sc-136290mouse IgG1N/AWB, IP, IFm, r, h
HDAC4 (B-5)sc-365093mouse IgG2b2-23 (h)WB, IP, IF, ELISAm, r, h, a
HDAC4 (A-4)sc-46672mouse IgG2b530-631(h)WB, IP, IF, IHC(P), ELISAm, h5
HDAC4 (F-6)sc-365367mouse IgG2a2-23 (h)WB, IP, IF, ELISAm, r, h, a1
HDAC4 (D-1)sc-48390mouse IgG1530-631 (h)WB, IP, IF, IHC(P), ELISAm, h
HDAC4 (H-92)sc-11418rabbit IgG530-631 (h)WB, IP, IF, IHC(P), ELISAm, r, h35
HDAC4 (L-19)sc-5246goat IgGN-terminal (h) WB, IP, IF, IHC(P), ELISAm, h, r, b7
HDAC4 (N-18)sc-5245goat IgGN-terminal (h) WB, IP, IF, IHC(P), ELISAm, h, r, a6
HDAC4 (HDAC-144)sc-56686mouse IgG2a1-19 (h)WB, IP, IFm, r, h
HDAC5 (B-11)sc-133106mouse IgG2b371-443 (h)WB, IP, IF, IHC(P), ELISAh, r2
HDAC5 (C-11)sc-133225mouse IgG2b371-443 (h)WB, IP, IF, IHC(P), ELISAm, r, h1
HDAC5 (G-18)sc-5250goat IgGinternal (h)WB, IP, IF, ELISAm, r, h7
HDAC5 (H-74)sc-11419rabbit IgG371-443 (h)WB, IP, IF, ELISAm, r, h, e, c, b14
HDAC5 (P-16)sc-5252goat IgGinternal (m)WB, IP, IF, IHC(P), ELISAm, r, h, e, c, b5
HDAC6 (D-11)sc-28386mouse IgG2a916-1215 (h)WB, IP, IF, IHC(P), ELISAhuman5
HDAC6 (H-300)sc-11420rabbit IgG916-1215 (h)WB, IP, IF, IHC(P), ELISAhuman39
HDAC6 (L-18)sc-5258goat IgGN-terminal (m)WB, IP, IF, IHC(P), ELISAm, r, h8
HDAC6 (S-14)sc-5255goat IgGN-terminal (h)WB, IP, IF, IHC(P), ELISAhuman3
HDAC4/5/7 (H-273)sc-11421rabbit IgG163-435 (h)WB, IP, IF, IHC(P), ELISAm, r, h15
HDAC7 (A-7)sc-74563mouse IgG2a163-435 (h)WB, IP, IF, ELISAhuman1
HDAC7 (L-19)sc-11493goat IgGinternal (m)WB, IP, IF, ELISAm, r > h
HDAC7 (C-18)sc-11491goat IgGC-terminal (h)WB, IP, IF, ELISAm, r, h6
HDAC7 (N-18)sc-11489goat IgGN-terminal (h)WB, IP, IF, IHC(P), ELISAm, r, h, c, b4
HDAC8 (B-4)sc-365620mouse IgG12-28 (h)WB, IP, IF, IHC(P), ELISAh > m, r
HDAC8 (E-5)sc-17778mouse IgG2b1-145 (h)WB, IP, IF, ELISAhuman6
HDAC8 (F-9)sc-374180mouse IgG32-28 (h)WB, IP, IF, ELISAh > m, r
HDAC8 (H-145)sc-11405rabbit IgG1-145 (h)WB, IP, IF, ELISAm, r, h, c, b, p, e16
HDAC8 (N-20)sc-11544goat IgGN-terminal (h)WB, IP, IF, ELISAh, e, c, b, p > m, r4
HDAC9 (B-1)sc-398003mouse IgM12-39 (h)WB, IP, IF, ELISAm, r, hNEW
HDAC8 (HDAC8-48)sc-56687mouse IgG1FL (h)WB, ELISAhuman
HDAC9 (H-45)sc-28732rabbit IgG1-45 (h)WB, IP, IF, ELISAm, r, h, e, c, p4
HDAC9 (G-15)sc-10408goat IgGN-terminal (h)WB, IF, ELISAm, r, h, e, c, b, p, a2
HDAC9 (N-20)sc-32094goat IgGN-terminal (h)WB, IP, IF, ELISAm, r, h, e, c, b, p, a
HDAC9 (P-17)sc-32095goat IgGinternal (h)WB, IF, ELISAm, r, h, e, c, b, p
HDAC9 (V-16)sc-30744goat IgGinternal (h)WB, IF, ELISAm, h, e, c, p, a
HDAC10 (D-9)sc-365270mouse IgG157-85 (h)WB, IP, IF, ELISAm, r, h1
HDAC10 (E-2)sc-393417mouse IgG2a62-116 (m)WB, IP, IF, ELISAm, hNEW
HDAC10 (F-4)sc-376121mouse IgG161-116 (h)WB, IP, IF, ELISAhuman
HDAC10 (H-56)sc-134995rabbit IgG61-116 (h)WB, IP, IF, ELISAh, e > m, r
HDAC10 (K-17)sc-54213goat IgGInternal (m)WB, IF, ELISAm, rNEW
HDAC10 (S-17)sc-54215goat IgGInternal (h)WB, IP, IF, ELISAhuman
HDAC10 (M-55)sc-134996rabbit IgG62-116 (m)WB, IP, IF, ELISAm, r > h
HDAC10 (N-20)sc-54214goat IgGN-terminal (h)WB, IF, ELISAm, r, hNEW
HDAC10 (Y-24)sc-130775rabbit IgGN/AWB, IP, ELISAm, h
HDAC11 (N-20)sc-54219goat IgGN-terminal (h)WB, IP, IF, ELISAm, r, h, e, b, p
HDAC11 (C-5)sc-390737mouse IgG2b (h)WB, IP, IF, ELISAhumanNEW
HDAC11 (S-15)sc-54220goat IgGN-terminal (h)WB, IF, ELISAm, r, h, e, b, p
HDAC11 (H-300)sc-292834rabbit IgG1-300 (h)WB, IP, IF, ELISAm, r, h
HDAC11 (Y-25)sc-130776rabbit IgGN/AWB, IP, IF, IHC(P), ELISAm, h1

Phospho-Specific HDAC Antibodies

p-HDAC2 (Ser 394)sc-135639rabbit IgGN/AWB, IP, IF, IHC(P)m, h2
p-HDAC4 (Ser 632)sc-101691rabbit IgGSer 632 (h)WB, IPm, r, h
p-HDAC5 (Ser 498)sc-101692rabbit IgGSer 498 (h)WB, IP, IF, IHC(P)m, h1
p-HDAC8 (Ser 39)sc-101693rabbit IgGSer 39 (h)IF, IHC(P)m, r, h1
p-HDAC4/5/9 (Ser 246/259/220)sc-135656rabbit IgGN/AWB, IPm, h

HDAC CRISPR/Cas9 Knockout Plasmids include:

HDAC1 CRISPR/Cas9 KO Plasmid (h)sc-400203gene knockouthumanNEW
HDAC2 CRISPR/Cas9 KO Plasmid (h)sc-400303gene knockouthumanNEW
HDAC6 CRISPR/Cas9 KO Plasmid (h)sc-400314gene knockouthumanNEW
HDAC4 CRISPR/Cas9 KO Plasmid (h)sc-400388gene knockouthumanNEW
HDAC3 CRISPR/Cas9 KO Plasmid (h)sc-400446gene knockouthumanNEW
HDAC5 CRISPR/Cas9 KO Plasmid (h)sc-400659gene knockouthumanNEW
HDAC8 CRISPR/Cas9 KO Plasmid (h)sc-400757gene knockouthumanNEW
HDAC7 CRISPR/Cas9 KO Plasmid (h)sc-400989gene knockouthumanNEW
HDAC9 CRISPR/Cas9 KO Plasmid (h)sc-401419gene knockouthumanNEW
HDAC11 CRISPR/Cas9 KO Plasmid (h)sc-402103gene knockouthumanNEW
HDAC10 CRISPR/Cas9 KO Plasmid (h)sc-403221gene knockouthumanNEW
HDAC1 CRISPR/Cas9 KO Plasmid (m)sc-436647gene knockoutmouseNEW
HDAC10 CRISPR/Cas9 KO Plasmid (m)sc-431327gene knockoutmouseNEW
HDAC11 CRISPR/Cas9 KO Plasmid (m)sc-433149gene knockoutmouseNEW
HDAC2 CRISPR/Cas9 KO Plasmid (m)sc-420817gene knockoutmouseNEW
HDAC3 CRISPR/Cas9 KO Plasmid (m)sc-420818gene knockoutmouseNEW
HDAC4 CRISPR/Cas9 KO Plasmid (m)sc-431586gene knockoutmouseNEW
HDAC5 CRISPR/Cas9 KO Plasmid (m)sc-420819gene knockoutmouseNEW
HDAC6 CRISPR/Cas9 KO Plasmid (m)sc-420820gene knockoutmouseNEW
HDAC7 CRISPR/Cas9 KO Plasmid (m)sc-425052gene knockoutmouseNEW
HDAC8 CRISPR/Cas9 KO Plasmid (m)sc-427666gene knockoutmouseNEW
HDAC9 CRISPR/Cas9 KO Plasmid (m)sc-429766gene knockoutmouseNEW

HDAC siRNA, shRNA Plasmid and shRNA Lentiviral Particles gene silencers include:

siRNAsshRNA PlasmidsshRNA Lentiviral ParticlesCITATIONSRANKING
HDAC1 siRNA (h): sc-29343HDAC1 shRNA Plasmid (h):
HDAC1 shRNA (h)
Lentiviral Particles: sc-29343-V
HDAC1 siRNA (h2): sc-44208HDAC1 shRNA Plasmid (h2):
HDAC1 shRNA (h2)
Lentiviral Particles: sc-44208-V
HDAC1 siRNA (m): sc-29344HDAC1 shRNA Plasmid (m):
HDAC1 shRNA (m)
Lentiviral Particles: sc-29344-V
HDAC1 siRNA (r): sc-270070HDAC1 shRNA Plasmid (r):
HDAC1 shRNA (r)
Lentiviral Particles: sc-270070-V
HDAC2 siRNA (h): sc-29345HDAC2 shRNA Plasmid (h):
HDAC2 shRNA (h)
Lentiviral Particles: sc-29345-V
HDAC2 siRNA (h2): sc-44262HDAC2 shRNA Plasmid (h2):
HDAC2 shRNA (h2)
Lentiviral Particles: sc-44262-V
HDAC2 siRNA (m): sc-29346HDAC2 shRNA Plasmid (m):
HDAC2 shRNA (m)
Lentiviral Particles: sc-29346-V
HDAC2 siRNA (r): sc-270150HDAC2 shRNA Plasmid (r):
HDAC2 shRNA (r)
Lentiviral Particles: sc-270150-V
Not Yet Rated
HDAC3 siRNA (h): sc-35538HDAC3 shRNA Plasmid (h):
HDAC3 shRNA (h)
Lentiviral Particles: sc-35538-V
HDAC3 siRNA (m): sc-35539HDAC3 shRNA Plasmid (m):
HDAC3 shRNA (m)
Lentiviral Particles: sc-35539-V
HDAC3 siRNA (r): sc-270161HDAC3 shRNA Plasmid (r):
HDAC3 shRNA (r)
Lentiviral Particles: sc-270161-V
HDAC4 siRNA (h): sc-35540HDAC4 shRNA Plasmid (h):
HDAC4 shRNA (h)
Lentiviral Particles: sc-35540-V
HDAC4 siRNA (m): sc-35541HDAC4 shRNA Plasmid (m):
HDAC4 shRNA (m)
Lentiviral Particles: sc-35541-V
HDAC5 siRNA (h): sc-35542HDAC5 shRNA Plasmid (h):
HDAC5 shRNA (h)
Lentiviral Particles: sc-35542-V
HDAC5 siRNA (m): sc-35543HDAC5 shRNA Plasmid (m):
HDAC5 shRNA (m)
Lentiviral Particles: sc-35543-V
HDAC6 siRNA (h): sc-35544HDAC6 shRNA Plasmid (h):
HDAC6 shRNA (h)
Lentiviral Particles: sc-35544-V
HDAC6 siRNA (m): sc-35545HDAC6 shRNA Plasmid (m):
HDAC6 shRNA (m)
Lentiviral Particles: sc-35545-V
HDAC7 siRNA (h): sc-35546HDAC7 shRNA Plasmid (h):
HDAC7 shRNA (h)
Lentiviral Particles: sc-35546-V
HDAC7 siRNA (m): sc-35547HDAC7 shRNA Plasmid (m):
HDAC7 shRNA (m)
Lentiviral Particles: sc-35547-V
HDAC8 siRNA (h): sc-35548HDAC8 shRNA Plasmid (h):
HDAC8 shRNA (h)
Lentiviral Particles: sc-35548-V
HDAC8 siRNA (h2): sc-44305HDAC8 shRNA Plasmid (h2):
HDAC8 shRNA (h2)
Lentiviral Particles: sc-44305-V
Not Yet Rated
HDAC8 siRNA (m): sc-35549HDAC8 shRNA Plasmid (m):
HDAC8 shRNA (m)
Lentiviral Particles: sc-35549-V
HDAC9 siRNA (h): sc-35550HDAC9 shRNA Plasmid (h):
HDAC9 shRNA (h)
Lentiviral Particles: sc-35550-V
HDAC9 siRNA (m): sc-35551HDAC9 shRNA Plasmid (m):
HDAC9 shRNA (m)
Lentiviral Particles: sc-35551-V
HDAC10 siRNA (h): sc-72307HDAC10 shRNA Plasmid (h):
HDAC10 shRNA (h)
Lentiviral Particles: sc-72307-V
HDAC10 siRNA (m): sc-72308HDAC10 shRNA Plasmid (m):
HDAC10 shRNA (m)
Lentiviral Particles: sc-72308-V
Not Yet Rated
HDAC11 siRNA (h): sc-106896HDAC11 shRNA Plasmid (h):
HDAC11 shRNA (h)
Lentiviral Particles: sc-106896-V
HDAC11 siRNA (m): sc-145909HDAC11 shRNA Plasmid (m):
HDAC11 shRNA (m)
Lentiviral Particles: sc-145909-V
HDAC11 siRNA (r): sc-156104HDAC11 shRNA Plasmid (r):
HDAC11 shRNA (r)
Lentiviral Particles: sc-156104-V
Not Yet Rated

In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, PCAF (p300/CBP-associated factor), p300/CBP, HAT1 and the TFIID subunit TAF II p250. There are several members of the histone deacetylases family.