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HDA4 AntibodiesSanta Cruz Biotechnology, Inc. offers a broad range of HDA4 antibodies. Select HDA4 antibodies from several monoclonal and/or polyclonal HDA4 antibodies listed below. View detailed HDA4 antibody specifications by linking to the specific product blocks. Select appropriate HDA4 antibodies for your research by isotype, epitope, applications and species reactivity. Introducing HOVERcruz™,a unique system for rapid identification of HDA4 Antibodies. Hover over product names in the table to see representative data for each product.Live chat is now available! (click here)Our live chat system is available to answer your product and ordering questions.
Remodeling of chromatin structure is believed to be a critical component of transcriptional regulation. A major source of remodeling is brought about by the acetylation of nucleosomal histones. Acetylation results in an allosteric change in the nucleosomal conformation and an increased accessibility of DNA to transcription factors. Conversely, the deacetylation of histones is associated with transcriptional silencing. HDA1, HDA2, HDA3, HDA4, HDA5, HDA6 and HDA7 have been identified as histone deacetylases in C. elegans and are homologous with histone deacetylase proteins in both yeast and mammalian systems. RBA1 and RBA2 are the C. elegans homologues of RbAp46 and RBAp48 respectively. RbAp46 and RbAp48 are Rb and histone binding proteins and are components of the histone deacetylase complex. |
