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GrpEL Antibodies

Santa Cruz Biotechnology, Inc. offers a broad range of GrpEL antibodies. Select GrpEL antibodies from several monoclonal and/or polyclonal GrpEL antibodies listed below. View detailed GrpEL antibody specifications by linking to the specific product blocks. Select appropriate GrpEL antibodies for your research by isotype, epitope, applications and species reactivity. GrpEL gene silencer products in siRNA, shRNA Plasmid and shRNA Lentiviral Particle formats are also available.

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a unique system for rapid identification of GrpEL Antibodies. Hover over product names in the table to see representative data for each product.

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PRODUCT NAMECAT. #ISOTYPEEPITOPEAPPLICATIONSSPECIESCITATIONSRATING
GrpEL1 (D-15)sc-242966goat IgGInternal (h)WB, IP, IF, ELISAm, r, hNEW
GrpEL2 (P-13)sc-164555goat IgGInternal (h)WB, IP, IF, ELISAm, r, h, e, c, bNEW
GrpEL2 (Y-14)sc-164557goat IgGInternal (h)WB, IP, IF, ELISAm, r, hNEW

GrpEL siRNA, shRNA Plasmid and shRNA Lentiviral Particles gene silencers include:

siRNAsshRNA PlasmidsshRNA Lentiviral ParticlesCITATIONSRANKING
GrpEL1 siRNA (h): sc-89323GrpEL1 shRNA Plasmid (h):
sc-89323-SH
GrpEL1 shRNA (h)
Lentiviral Particles: sc-89323-V
GrpEL1 siRNA (m): sc-145781GrpEL1 shRNA Plasmid (m):
sc-145781-SH
GrpEL1 shRNA (m)
Lentiviral Particles: sc-145781-V
GrpEL2 siRNA (h): sc-91628GrpEL2 shRNA Plasmid (h):
sc-91628-SH
GrpEL2 shRNA (h)
Lentiviral Particles: sc-91628-V
GrpEL2 siRNA (m): sc-145782GrpEL2 shRNA Plasmid (m):
sc-145782-SH
GrpEL2 shRNA (m)
Lentiviral Particles: sc-145782-V

GrpEL2 (GrpE protein homolog 2) is a 225 amino acid mitochondrial matrix protein and component of the PAM complex. Consisting of Tim44, Tim14, HSP 70, Magmas, GrpEL1 and GrpEL2, the PAM complex plays an essential role in the ATP-dependent translocation of transit peptide-containing proteins to the mitochondrial matrix from the inner membrane. GrpEL2 regulates the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins and stimulates its ATPase activity. The gene encoding GrpEL2 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.