GAP Antibodies

Santa Cruz Biotechnology, Inc. offers a broad range of GAP antibodies. Select GAP antibodies from several monoclonal and/or polyclonal GAP antibodies listed below. View detailed GAP antibody specifications by linking to the specific product blocks. Select appropriate GAP antibodies for your research by isotype, epitope, applications and species reactivity. GAP gene silencer products in siRNA, shRNA Plasmid and shRNA Lentiviral Particle formats are also available.

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Also see additional GAP Antibodies including, GAP-assoc p190, GAP1-InsP4 BP, Gap1, GAP1m, Gap 1

PRODUCT NAME	CAT. #	ISOTYPE	EPITOPE	APPLICATIONS	SPECIES	CITATIONS
GAP1-InsP₄ BP (H-6)	sc-374555	mouse IgG₁	801-830 (h)	WB, IP, IF, ELISA	m, r, h
GAP1-InsP₄ BP (G-9)	sc-166442	mouse IgG₁	2-31 (h)	WB, IP, IF, IHC(P), ELISA	m, r, h
GAP1-InsP₄ BP (C-20)	sc-17946	goat IgG	C-terminus (h)	WB, IP, IF, ELISA	m, r, h, e, c, b, p, a
GAP1-InsP₄ BP (N-14)	sc-34467	goat IgG	N-terminus (h)	WB, IP, IF, ELISA	m, r, h, c, a
GAP1-InsP₄ BP (N-18)	sc-34468	goat IgG	N-terminus (h)	WB, IP, IF, ELISA	m, r, h, e, c, b, p, a
GAP1^m (C-17)	sc-8702	goat IgG	C-terminus (h)	WB, IP, IF, ELISA	m, r, h, e, c, p
GAP1^m (N-19)	sc-8701	goat IgG	N-terminus (h)	WB, IF, ELISA	m, r, h, b
GAP1^m (15)	sc-135916	mouse IgG₁	N/A	WB, IF	m, r, h
GAP-assoc p190 (C-20)	sc-518	rabbit IgG	C-terminus (r)	WB, IF, ELISA	r	1

Non-Mammalian GAP Antibodies

PRODUCT NAME	CAT. #	ISOTYPE	EPITOPE	APPLICATIONS	SPECIES	CITATIONS	RATING
Gap 1 (Y-40)	sc-98846	rabbit IgG	1-40 (Sc)	WB, IP, IF, ELISA	S. cerevisiae
Gap1 (yF-15)	sc-26303	goat IgG	C-terminus (Sc)	WB, ELISA	S. cerevisiae

GAP siRNA, shRNA Plasmid and shRNA Lentiviral Particles gene silencers include:

siRNAs	shRNA Plasmids	shRNA Lentiviral Particles
GAP1-InsP₄ BP siRNA (h): sc-39023	GAP1-InsP₄ BP shRNA Plasmid (h): sc-39023-SH	GAP1-InsP₄ BP shRNA (h) Lentiviral Particles: sc-39023-V
GAP1-InsP₄ BP siRNA (m): sc-39024	GAP1-InsP₄ BP shRNA Plasmid (m): sc-39024-SH	GAP1-InsP₄ BP shRNA (m) Lentiviral Particles: sc-39024-V
GAP1^m siRNA (h): sc-41704	GAP1^m shRNA Plasmid (h): sc-41704-SH	GAP1^m shRNA (h) Lentiviral Particles: sc-41704-V
GAP1^m siRNA (m): sc-41705	GAP1^m shRNA Plasmid (m): sc-41705-SH	GAP1^m shRNA (m) Lentiviral Particles: sc-41705-V

Human GAP1-InsP⁴ BP binds phospholipids in both a calcium-dependent and independent manner. GAP1, one of the Ras GTPase-activating protein families, comprises four distinct genes, including GAP1(m), GAP1-InsP⁴ BP, MRASAL (murine Ras GTPase-activating-like) and KIAA0538. This family contains an N-terminal tandem C2 domain, a GAP-related domain and a C-terminal pleckstrin homology (PH) domain. The PH domains of GAP1-InsP⁴ BP are essential for membrane targeting via binding of specific phospholipids. In mitogenically activated and tyrosine kinase-transformed cells, Ras GAP forms a complex with a protein designated p190. p190 at its amino terminus contains sequence motifs characteristic of all known GTPases while the carboxy terminal domain contains sequences similar to those found in the Bcr gene product and n-chimeric and Rho GAP, all of which exhibit intrinsic GAP activity. In addition, the central domain of p190 contains a sequence nearlyidentical to that of the transcriptional repressor, GRF-1.