Estrogen Receptor Antibodies

Santa Cruz Biotechnology, Inc. offers a broad range of Estrogen Receptor antibodies. Select Estrogen Receptor antibodies from several monoclonal and/or polyclonal Estrogen Receptor antibodies listed below. View detailed Estrogen Receptor antibody specifications by linking to the specific product blocks. Select appropriate Estrogen Receptor antibodies for your research by isotype, epitope, applications and species reactivity. Estrogen Receptor gene silencer products in siRNA, shRNA Plasmid and shRNA Lentiviral Particle formats are also available.

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See Estrogen Receptor Inhibitors, Estrogen Receptor Activators or Estrogen Receptor Substrates for functional analysis of cellular responses to Estrogen Receptor.

Also see additional Estrogen Receptor Antibodies including, ER alpha, ER beta, ERR alpha, ERR beta, ERR gamma

Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including ERα and ERβ, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. They are located in the nucleus , though some estrogen receptors associate with the cell surface membrane and can be rapidly activated by exposure of cells to estrogen. ERα and ERβ have been shown to be differentially activated by various ligands. Receptor-ligand interactions trigger a cascade of events, including dissociation from heat shock proteins, receptor dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes. Evidence suggests that ERα and ERβ may be regulated by distinct mechanisms even though they share many functional characteristics.