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Ero1 AntibodiesSanta Cruz Biotechnology, Inc. offers a broad range of Ero1 antibodies. Select Ero1 antibodies from several monoclonal and/or polyclonal Ero1 antibodies listed below. View detailed Ero1 antibody specifications by linking to the specific product blocks. Select appropriate Ero1 antibodies for your research by isotype, epitope, applications and species reactivity. Ero1 gene silencer products in siRNA, shRNA Plasmid and shRNA Lentiviral Particle formats are also available. Introducing HOVERcruz™,a unique system for rapid identification of Ero1 Antibodies. Hover over product names in the table to see representative data for each product.Live chat is now available! (click here)Our live chat system is available to answer your product and ordering questions.Also see additional Ero1 Antibodies including, Ero1-L beta, Ero1-L alpha
Ero1 siRNA, shRNA Plasmid and shRNA Lentiviral Particles gene silencers include:
Catalysis of disulfide bond formation is an integral component of protein biogenesis in the secretory pathway. Conserved between yeast and mammals, endoplasmic reticulum oxidoreductases (EROs) are essential for the formation of disulfide bonds. Ero1-Lβ (endoplasmic oxidoreductin-1-like protein B), also known as oxidoreductin-1-L-β, is a 467 amino acid protein that localizes to the endoplasmic reticulum and belongs to the ERO family. Ero1-Lβ is widely expressed at low levels but is greatly enriched in pancreas and in lower digestive tract. Ero1-Lβ, along with Ero1-Lα, transfer oxidative analogs to protein disulfide isomerase (PDI), which in turn oxidizes cargo proteins. Regulated by glutathione and induced by unfolded protein response (UPR), Ero1-Lβ promotes insulin biogenesis and glucose homeostasis. Ero1-Lβ exists as both a monomer and homodimer. |
