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DUX AntibodiesSanta Cruz Biotechnology, Inc. offers a broad range of DUX antibodies. Select DUX antibodies from several monoclonal and/or polyclonal DUX antibodies listed below. View detailed DUX antibody specifications by linking to the specific product blocks. Select appropriate DUX antibodies for your research by isotype, epitope, applications and species reactivity. DUX gene silencer products in siRNA, shRNA Plasmid and shRNA Lentiviral Particle formats are also available. Introducing HOVERcruz™,a unique system for rapid identification of DUX Antibodies. Hover over product names in the table to see representative data for each product.Live chat is now available! (click here)Our live chat system is available to answer your product and ordering questions.Also see additional DUX Antibodies including, DUX1, DUX2, DUX3, DUX4, DUX5
DUX siRNA, shRNA Plasmid and shRNA Lentiviral Particles gene silencers include:
The double homeobox (DUX) proteins are encoded by 3.3-kilobase repeats found throughout the human genome. The DUX family includes DUX1, DUX2, DUX3, DUX4 and DUX5. Each of these family members contain two homeobox domains except DUX2, which contains only one homeobox domain. DUX1 and DUX5 are identical to one another and share 98% identity with DUX3 and approximately 70% identity with DUX2. The homeodomains found in DUX5 and DUX1 are similar to those found in Pax-3, Pax-7, OTX1 and OTX2. The genes encoding DUX5 and DUX3 both contain additional start sites that result in N-terminal extended isoforms. DUX4, also known as DUX10, is capable of forming homodimers. In addition, the gene encoding DUX4 maps within the D4Z4 repeat unit that has been implicated in Facioscapulohumeral muscular dystrophy (FSHD). |
