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DISP AntibodiesSanta Cruz Biotechnology, Inc. offers a broad range of gene silencers in the form of siRNAs, shRNA Plasmids and shRNA Lentiviral Particles. DISP gene silencers are available as DISP siRNA, DISP shRNA Plasmid and DISP shRNA Lentiviral Particles. Gene silencers are useful for gene studies in combination with antibodies used for protein detection. Introducing HOVERcruz™,a unique system for rapid identification of DISP Antibodies. Hover over product names in the table to see representative data for each product.Live chat is now available! (click here)Our live chat system is available to answer your product and ordering questions.
DISP2 (protein dispatched homolog 2), also known as DISPB or KIAA1742, is a 1,401 amino acid multi-pass membrane protein. A member of the dispatched family, DISP2 contains a putative sterol-sensing (SSD) domain. The SSD domain has been identified in key regulatory genes in cholesterol homeostasis and lipoprotein signaling. The gene encoding DISP2 maps to human chromosome 15q15.1. Encoding more than 700 genes, chromosome 15 is made up of approximately 106 million base pairs and comprises about 3% of the human genome. Tay-Sachs disease is a lethal disorder associated with mutations in the HEXA gene, which is encoded by chromosome 15. Marfan syndrome is also associated with chromosome 15 through the FBN1 gene. |