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D4DR Antibodies

Santa Cruz Biotechnology, Inc. offers a broad range of D4DR antibodies. Select D4DR antibodies from several monoclonal and/or polyclonal D4DR antibodies listed below. View detailed D4DR antibody specifications by linking to the specific product blocks. Select appropriate D4DR antibodies for your research by isotype, epitope, applications and species reactivity. D4DR gene silencer products in siRNA, shRNA Plasmid and shRNA Lentiviral Particle formats are also available.

Introducing HOVERcruz™,

a unique system for rapid identification of D4DR Antibodies. Hover over product names in the table to see representative data for each product.

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See D4DR Inhibitors or D4DR Activators for functional analysis of cellular responses to D4DR.

PRODUCT NAMECAT. #ISOTYPEEPITOPEAPPLICATIONSSPECIESCITATIONSRATING
D4DR (H-50)sc-25649rabbit IgG141-190 (h)WB, IP, IF, ELISAm, r, h, e, c, p1
D4DR (N-20)sc-31480goat IgGN-terminal (h)WB, IP, IF, ELISAh > m, r1
D4DR (R-20)sc-1439goat IgGC-terminus (r)WB, IP, IF, ELISAm, r, h, p3
D4DR (2B9)sc-136169mouse IgG176-185 (h)WB, IP, IFm, r, h2
D4DR (D-16)sc-31481goat IgGextracellular (h)WB, IP, IF, ELISAm, r, h, e, c, p

D4DR siRNA, shRNA Plasmid and shRNA Lentiviral Particles gene silencers include:

siRNAsshRNA PlasmidsshRNA Lentiviral ParticlesCITATIONSRANKING
D4DR siRNA (h): sc-41932D4DR shRNA Plasmid (h):
sc-41932-SH
D4DR shRNA (h)
Lentiviral Particles: sc-41932-V
D4DR siRNA (m): sc-41933D4DR shRNA Plasmid (m):
sc-41933-SH
D4DR shRNA (m)
Lentiviral Particles: sc-41933-V

Members of the G protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven- transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. β-adrenergic receptor binds to adrenaline activates adenylyl cyclase, while α2-adrenergic receptor binds to adrenaline and inhibits adenylyl cyclase. The dopamine receptors are divided into two classes, D1 and D2, which differ in their functional characteristics in that D1 receptors stimulate adenylyl cyclase, while D2 receptors inhibit adenylyl cyclase activity. Five different subtypes of dopamine receptor have been described to date. D1DR and D5DR belong to the D1 subclass, while D2DR, D3DR and D4DR belong to the D2 subclass of dopamine receptors.