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CTAGE AntibodiesSanta Cruz Biotechnology, Inc. offers a broad range of CTAGE antibodies. Select CTAGE antibodies from several monoclonal and/or polyclonal CTAGE antibodies listed below. View detailed CTAGE antibody specifications by linking to the specific product blocks. Select appropriate CTAGE antibodies for your research by isotype, epitope, applications and species reactivity. CTAGE gene silencer products in siRNA, shRNA Plasmid and shRNA Lentiviral Particle formats are also available. Introducing HOVERcruz™,a unique system for rapid identification of CTAGE Antibodies. Hover over product names in the table to see representative data for each product.Live chat is now available! (click here)Our live chat system is available to answer your product and ordering questions.Also see additional CTAGE Antibodies including, CTAGE1, CTAGE2, CTAGE3, CTAGE4, CTAGE5, CTAGE6, CTAGE9... See More
CTAGE siRNA, shRNA Plasmid and shRNA Lentiviral Particles gene silencers include:
Cutaneous T-cell lymphomas (CTCL) represent a group of skin neoplasms that originate from T lymphocytes and are difficult to treat in advanced stages. Cutaneous T-cell lymphoma-associated antigen 1 (CTAGE1) is normally expressed only in testis tissue, and is found in 35% of CTCL tissues, but not in any leukemia or melanoma cell lines. CTAGE2 is a longer variant of CTAGE1 and is translated from a different open reading frame. CTAGE2, under normal conditions, are found primarily in the testis with little or no expression in other parts of the body. Another member of the CTAG family, namely CTAGE5 is a tumor associated antigen that is found in tumors of various origins, including cutaneous T cell lymphomas. CTAGE3 is expressed in normal tissues including colon, mammary gland, ovary, placenta, stomach and testis, as well as several fetal tissues. CTAGE3 has been detected in mycosis fungoides tissues and T-zone lymphomas. This evidence suggests a potential role for CTAGE3 in the immunotherapy of cutaneous T-cell lymphomas and other malignancies. |
