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CHRNB4 AntibodiesSanta Cruz Biotechnology, Inc. offers a broad range of CHRNB4 antibodies. Select CHRNB4 antibodies from several monoclonal and/or polyclonal CHRNB4 antibodies listed below. View detailed CHRNB4 antibody specifications by linking to the specific product blocks. Select appropriate CHRNB4 antibodies for your research by isotype, epitope, applications and species reactivity. CHRNB4 gene silencer products in siRNA, shRNA Plasmid and shRNA Lentiviral Particle formats are also available. Introducing HOVERcruz™,a unique system for rapid identification of CHRNB4 Antibodies. Hover over product names in the table to see representative data for each product.Live chat is now available! (click here)Our live chat system is available to answer your product and ordering questions.See CHRNB4 Inhibitors or CHRNB4 Activators for functional analysis of cellular responses to CHRNB4.
CHRNB4 siRNA, shRNA Plasmid and shRNA Lentiviral Particles gene silencers include:
Members of the ligand-gated ion channel receptor family are characterized by their fast transmitting response to neurotransmitters. Two important members of this family are the nicotinic acetylcholine and glutamate receptors, both of which are composed of five homologous subunits forming a transmembrane aqueous pore. These transmembrane receptors change conformation in response to their cognate neurotransmitter. Nicotinic acetylcholine receptors (AChRs) are found at the postsynaptic membrane of the neuromuscular junction and bind acetylcholine molecules, allowing ions to move through the pore. Glutamate receptors are found in the postsynaptic membrane of cells in the central nervous system. The activity that is generated at the synapse by the binding of acetylcholine is terminated by acetylcholinesterase, an enzyme that rapidly hydrolyzes acetylcholine. CHRNB4 (cholinergic receptor, nicotinic, β 4) is a 498 amino acid member of the ligand-gated ionic channel family. CHRNB4 plays a role in the glutamatergic pathway and my be associated with nicotine dependence. |
