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CD8 AntibodiesSanta Cruz Biotechnology, Inc. offers a broad range of CD8 antibodies. Select CD8 antibodies from several monoclonal and/or polyclonal CD8 antibodies listed below. View detailed CD8 antibody specifications by linking to the specific product blocks. Select appropriate CD8 antibodies for your research by isotype, epitope, applications and species reactivity. CD8 gene silencer products in siRNA, shRNA Plasmid and shRNA Lentiviral Particle formats are also available. Introducing HOVERcruz™,a unique system for rapid identification of CD8 Antibodies. Hover over product names in the table to see representative data for each product.Live chat is now available! (click here)Our live chat system is available to answer your product and ordering questions.Also see additional CD8 Antibodies including, CD8-alpha, CD8-beta
CD8 siRNA, shRNA Plasmid and shRNA Lentiviral Particles gene silencers include:
The T cell receptor (TCR) is a heterodimer composed of either α and β or γ and δ chains. CD3 chains and the CD4 or CD8 co-receptors are also required for efficient signal transduction through the TCR. The TCR is expressed on T helper and T cytotoxic cells that can be distinguished by their expression of CD4 and CD8; T helper cells express CD4 proteins and T cytotoxic cells display CD8. CD8 (also designated Leu 2 or T8), a cell surface glycoprotein, is a two chain complex (αα or αβ) receptor that binds class I MHC molecules presented by the antigen-presenting cell (APC). A primary function of CD8 is to facilitate antigen recognition by the TCR and to strengthen the avidity of the TCR-antigen interactions. An additional role for CD8-expressing T cells may be to maintain low levels of HIV expression. |
