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C17orf89 AntibodiesSanta Cruz Biotechnology, Inc. offers a broad range of C17orf89 antibodies. Select C17orf89 antibodies from several monoclonal and/or polyclonal C17orf89 antibodies listed below. View detailed C17orf89 antibody specifications by linking to the specific product blocks. Select appropriate C17orf89 antibodies for your research by isotype, epitope, applications and species reactivity. C17orf89 gene silencer products in siRNA, shRNA Plasmid and shRNA Lentiviral Particle formats are also available. Introducing HOVERcruz™,a unique system for rapid identification of C17orf89 Antibodies. Hover over product names in the table to see representative data for each product.Live chat is now available! (click here)Our live chat system is available to answer your product and ordering questions.
C17orf89 siRNA, shRNA Plasmid and shRNA Lentiviral Particles gene silencers include:
C17orf89 (chromosome 17 open reading frame 89) is a 74 amino acid protein that is encoded by a gene mapping to human chromosome 17. Chromosome 17 makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17. |
