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Bystin AntibodiesSanta Cruz Biotechnology, Inc. offers a broad range of Bystin antibodies. Select Bystin antibodies from several monoclonal and/or polyclonal Bystin antibodies listed below. View detailed Bystin antibody specifications by linking to the specific product blocks. Select appropriate Bystin antibodies for your research by isotype, epitope, applications and species reactivity. Bystin gene silencer products in siRNA, shRNA Plasmid and shRNA Lentiviral Particle formats are also available. Introducing HOVERcruz™,a unique system for rapid identification of Bystin Antibodies. Hover over product names in the table to see representative data for each product.Live chat is now available! (click here)Our live chat system is available to answer your product and ordering questions.
Bystin siRNA, shRNA Plasmid and shRNA Lentiviral Particles gene silencers include:
Bystin (or Bystin-like) is an evolutionarily conserved protein from yeast to humans. It localizes to the nucleolus and cytoplasm. Nuclear Bystin associates with the 40S ribosomal subunit and cytoplasmic Bystin directly binds Trophinin and Tastin, facilitating the adhesion of cells expressing these proteins. Knockdown of Bystin inhibits cell proliferation and delays RNA processing of the 18S component of the 40S ribosomal subunit. This suggests that Bystin plays an important role in ribosome biogenesis. In addition, embryo development is arrested around the 16-cell stage when Bystin expression is knocked down. This implies that Bystin is important for the development of preimplantation embryos. Bystin is also overexpressed in human cancers providing further evidence suggesting that it participates in cell proliferation. |
