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Axin Interactor AntibodiesSanta Cruz Biotechnology, Inc. offers a broad range of Axin Interactor antibodies. Select Axin Interactor antibodies from several monoclonal and/or polyclonal Axin Interactor antibodies listed below. View detailed Axin Interactor antibody specifications by linking to the specific product blocks. Select appropriate Axin Interactor antibodies for your research by isotype, epitope, applications and species reactivity. Axin Interactor gene silencer products in siRNA, shRNA Plasmid and shRNA Lentiviral Particle formats are also available. Introducing HOVERcruz™,a unique system for rapid identification of Axin Interactor Antibodies. Hover over product names in the table to see representative data for each product.Live chat is now available! (click here)Our live chat system is available to answer your product and ordering questions.Also see additional Axin Interactor Antibodies including, axin interactor 1
Axin Interactor siRNA, shRNA Plasmid and shRNA Lentiviral Particles gene silencers include:
AIDA (Axin interactor, dorsalization associated protein), also known as C1orf80, is a 306 amino acid protein that belongs to the axin interactor family. Expressed in a variety of tissues, including skeletal muscle and heart, AIDA functions as a ventralizing factor during embryogenesis, disrupting Axin homodimerization and inhibiting Axin-mediated JNK activation. Axin, a scaffold protein, is important for both JNK signaling and the canonical Wnt pathway, two processes that play an essential role in embryonic dorsoventral patterning. Disruption of Axin by AIDA results in the negative regulation of JNK and Wnt signaling, thereby affecting embryonic developmental events. Three isoforms of AIDA exist due to alternative splicing events. |
