Atm Antibodies
| PRODUCT NAME |
CATALOG # |
ISOTYPE |
EPITOPE |
APPLICATIONS |
SPECIES |
| Atm (H-248) Antibody |
sc-7230 |
rabbit IgG |
2830-3056 (h) |
WB, IP, IF, ELISA |
m, r, h, e, c, b, p, a |
| Atm (2C1) Antibody |
sc-23921 |
mouse IgG1 |
2577-3056 (h) |
WB, IP, IF |
m, r, h |
| Atm (ATM 11G12) Antibody |
sc-53173 |
mouse IgG1 |
992-1144 (h) |
WB, IP, IF |
human |
| Atm (C-20) Antibody |
sc-1212 |
goat IgG |
C-terminus (h) |
WB, IP, IF, ELISA |
m, r, h, e, c, b, a |
| Atm (H-280) Antibody |
sc-15392 |
rabbit IgG |
2581-2860 (h) |
WB, IP, IF, ELISA |
m, r, h, e, c, b, p |
| Atm (H-300) Antibody |
sc-28881 |
rabbit IgG |
1-300 (h) |
WB, IP, IF, ELISA |
m, r, h, e, c, b, p |
| Atm (K-19) Antibody |
sc-1214 |
goat IgG |
C-terminus (h) |
WB, IP, IF, ELISA |
m, r, h, e, c, b, p, a |
| Atm (N-17) Antibody |
sc-1213 |
goat IgG |
central (h) |
WB, IP, IF, ELISA |
h, e, c |
| Atm (Q-19) Antibody |
sc-7129 |
goat IgG |
N-terminus (h) |
WB, IP, IF, ELISA |
m, r, h, c |
| Atm (R-18) Antibody |
sc-7128 |
goat IgG |
internal (h) |
WB, IP, IF, ELISA |
h, e, b, p |
| Atm (1A1) Antibody |
sc-73615 |
mouse IgG1 |
2581-2860 (h) |
WB, IP, IF |
m, r, h |
| Atm (1B10) Antibody |
sc-135663 |
mouse IgG2b |
N/A |
WB, IP, ELISA |
m, r, h |
| Atm (5C2) Antibody |
sc-23922 |
mouse IgG1 |
980-1512 (h) |
WB, IP, IF |
m, r, h |
| p-Atm (10H11.E12) Antibody |
sc-47739 |
mouse IgG1 |
Ser 1981 (h) |
WB, IP, IF |
m, h |
Atm specific siRNA, sHRNA Plasmid and shRNA Lentiviral Particles gene silencers are also available.
These include:
BACKGROUND
The phosphatidylinositol kinase (PIK) family members fall into two distinct subgroups. The first subgroup contains proteins such as the PI 3- and PI 4-kinases and the second group comprises the PIK-related kinases. The PIK-related kinases include Atm, DNA-PKCS and FRAP. These proteins have in common a region of homology at their carboxy termini that is not present in the PI 3- and PI 4-kinases. All of the members of the PIK-related kinases are also larger than 270 kDa. The Atm gene is mutated in the autosomal recessive disorder ataxia telangiectasia (AT) that is characterized by cerebellar degeneration (ataxia) and the appearance of dilated blood vessels (telangiectases) in the conjunctivae of the eyes. AT cells are hypersensitive to ionizing radiation, impaired in mediating the inhibition of DNA synthesis and they display delays in p53 induction.
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