Ankyrin Antibodies

PRODUCT NAME	CATALOG #	ISOTYPE	EPITOPE	APPLICATIONS	SPECIES
Ankyrin-1 (D-3) Antibody	sc-374105	mouse IgG₁	820-952 (h)	WB, IP, IF, ELISA	human
Ankyrin-1 (H-125) Antibody	sc-135329	rabbit IgG	787-911 (h)	WB, IP, IF, ELISA	m, r, h, e
Ankyrin-1 (H-4) Antibody	sc-374240	mouse IgG_2a	820-952 (h)	WB, IP, IF, ELISA	human
Ankyrin B (C-20) Antibody	sc-30519	goat IgG	C-terminal (h)	WB, IF, ELISA	h > m
Ankyrin B (D-20) Antibody	sc-30517	goat IgG	C-terminus (h)	WB, IF, ELISA	m, r, h, e, b, p, a
Ankyrin B (H-300) Antibody	sc-28560	rabbit IgG	C-terminus (h)	WB, IP, IF, ELISA	m, r, h
Ankyrin B (G-11) Antibody	sc-365757	mouse IgG₁	3625-3924 (h)	WB, IP, IF, ELISA	human
Ankyrin B (V-18) Antibody	sc-14995	goat IgG	C-terminus (h)	WB, IF, ELISA	m, r, h
Ankyrin B (2.20) Antibody	sc-12718	mouse IgG₁	FL (h)	WB, IP, IF	m, r, h
Ankyrin B (3G7) Antibody	sc-70358	mouse IgG₁	FL (h)	WB, IP, IF	m, r, h
Ankyrin G (H-215) Antibody	sc-28561	rabbit IgG	C-terminus (h)	WB, IP, IF, IHC(P), ELISA	m, r, h, c, e, p
Ankyrin G (A-7) Antibody	sc-137105	mouse IgG₁	4163-4377 (h)	WB, IP, IF, ELISA	h, r
Ankyrin G (H-4) Antibody	sc-166602	mouse IgG_2b	4163-4377 (h)	WB, IP, IF, ELISA	human
Ankyrin G (P-20) Antibody	sc-31778	goat IgG	C-terminus (h)	WB, IP, IF, ELISA	m, r, h, c, b, p, a, e
Ankyrin G (T-14) Antibody	sc-31776	goat IgG	Internal (h)	WB, IF, ELISA	m, r, h, e, c, b, p
Ankyrin G (3G8) Antibody	sc-70359	mouse IgG₁	FL (h)	WB, IP, IF	h > r
Ankyrin G (463) Antibody	sc-12719	mouse IgG₁	FL (h)	WB, IP, IF	m, r, h
Ankyrin-1 (8C3) Antibody	sc-12733	mouse IgG₁	FL (h)	WB, IP, IF, IHC(P), ELISA	m, h
Ankyrin-1 (K-20) Antibody	sc-87551	rabbit IgG	Internal (h)	WB, IF, ELISA	m, r, h, e, c, b, p
Ankyrin-1 (N-13) Antibody	sc-87552	rabbit IgG	Internal (h)	WB, IF, ELISA	m, r, h, e, c, b, p, a

Ankyrin specific siRNA, sHRNA Plasmid and shRNA Lentiviral Particles gene silencers are also available.

These include:

siRNAs	shRNA Plasmids	shRNA Lentiviral Particles
Ankyrin B siRNA (h): sc-29680	Ankyrin B shRNA Plasmid (h): sc-29680-SH	Ankyrin B shRNA (h) Lentiviral Particles: sc-29680-V
Ankyrin B siRNA (m): sc-29681	Ankyrin B shRNA Plasmid (m): sc-29681-SH	Ankyrin B shRNA (m) Lentiviral Particles: sc-29681-V
Ankyrin G siRNA (h): sc-43263	Ankyrin G shRNA Plasmid (h): sc-43263-SH	Ankyrin G shRNA (h) Lentiviral Particles: sc-43263-V
Ankyrin G siRNA (m): sc-43268	Ankyrin G shRNA Plasmid (m): sc-43268-SH	Ankyrin G shRNA (m) Lentiviral Particles: sc-43268-V
Ankyrin-1 siRNA (h): sc-43615	Ankyrin-1 shRNA Plasmid (h): sc-43615-SH	Ankyrin-1 shRNA (h) Lentiviral Particles: sc-43615-V
Ankyrin-1 siRNA (m): sc-43262	Ankyrin-1 shRNA Plasmid (m): sc-43262-SH	Ankyrin-1 shRNA (m) Lentiviral Particles: sc-43262-V

BACKGROUND
Members of the Ankyrin family are membrane skeletal proteins that sort to distinct sites on the plasma membrane of cells. Both Ankyrin B and Ankyrin G are essential for normal neuronal functions. Specifically, Ankyrin B associates with the spectrin-actin network, mediates axon fasciculation, and stabilizes axon bundles. Ankyrin G localizes to the nodes of Ranvier and axon initial segments to mediate normal neuronal sodium channel function.