Welcome to Santa Cruz Biotechnology!

AIF Antibodies

Santa Cruz Biotechnology, Inc. offers a broad range of AIF antibodies. Select AIF antibodies from several monoclonal and/or polyclonal AIF antibodies listed below. View detailed AIF antibody specifications by linking to the specific product blocks. Select appropriate AIF antibodies for your research by isotype, epitope, applications and species reactivity. AIF gene silencer products in siRNA, shRNA Plasmid, shRNA Lentiviral Particle, CRISPR/Cas9 Knockout and CRISPR Double Nickase Plasmid formats are also available as well as CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems for gene activation.

Introducing HOVERcruz™,

a unique system for rapid identification of AIF Antibodies. Hover over the icon next to the product names in the table to see representative data for that product.

Live chat is now available! (click here)

Our live chat system is available to answer your product and ordering questions.

Also see additional AIF Antibodies including, AIFL

PRODUCT NAMECAT. #ISOTYPEEPITOPEAPPLICATIONSSPECIESCITATIONSRATING
AIF (B-9)
sc-55519mouse IgG2a1-300 (h)WB, IP, IF, IHC(P), ELISAm, h5
AIF (D-20)
sc-9416goat IgGC-terminal (m)WB, IP, IF, IHC(P), ELISAm, r, h, e, c, b, p, a49
AIF (E-1)
sc-13116mouse IgG2b1-300 (h) WB, IP, IF, IHC(P), FCM, ELISAm, r, h75
AIF (E-11)
sc-390619mouse IgM586-612 (m)WB, IP, IF, ELISAm, r, h, e, c, b, pNEW
AIF (N-19)
sc-9417goat IgGN-terminal (h)WB, IP, IF, IHC(P), ELISAh, e, c, b, p > m6
AIF (H-300)
sc-5586rabbit IgG1-300 (h)WB, IP, IF, ELISAm, r, h, e, c, b, p38
AIFL (A-9)
sc-376570mouse IgG11-300 (h)WB, IP, IF, ELISAhuman
AIFL (H-300)
sc-292446rabbit IgG1-300 (h)WB, IP, IF, ELISAm, r, h
AIFL (K-14)
sc-86277rabbit IgGInternal (h)WB, IP, IF, ELISAm, r, h, e, c, b, p
AIFL (Q-14)
sc-86279rabbit IgGInternal (h)WB, IP, IF, ELISAm, r, h, e, b, p

AIF CRISPR Knockout, HDR and Nickase Knockout Plasmids include:

PRODUCT NAMECAT. #SPECIESAPPLICATIONSMARKERCITATIONS
AIF CRISPR/Cas9 KO Plasmid (h)
sc-400370humanGene KnockoutGFPNEW
AIF HDR Plasmid (h)
sc-400370-HDRhumanHomology Directed RepairPuromycinNEW
AIF Double Nickase Plasmid (h)
sc-400370-NIChumanGene KnockoutPuromycinNEW
AIF Double Nickase Plasmid (h2)
sc-400370-NIC-2humanGene KnockoutPuromycinNEW
AIFL CRISPR/Cas9 KO Plasmid (h)
sc-414674humanGene KnockoutGFPNEW
AIFL HDR Plasmid (h)
sc-414674-HDRhumanHomology Directed RepairPuromycinNEW
AIFL Double Nickase Plasmid (h)
sc-414674-NIChumanGene KnockoutPuromycinNEW
AIFL Double Nickase Plasmid (h2)
sc-414674-NIC-2humanGene KnockoutPuromycinNEW
AIF CRISPR/Cas9 KO Plasmid (m)
sc-424143mouseGene KnockoutGFPNEW
AIF HDR Plasmid (m)
sc-424143-HDRmouseHomology Directed RepairPuromycinNEW
AIF Double Nickase Plasmid (m)
sc-424143-NICmouseGene KnockoutPuromycinNEW
AIF Double Nickase Plasmid (m2)
sc-424143-NIC-2mouseGene KnockoutPuromycinNEW
AIFL CRISPR/Cas9 KO Plasmid (m)
sc-428262mouseGene KnockoutGFPNEW
AIFL HDR Plasmid (m)
sc-428262-HDRmouseHomology Directed RepairPuromycinNEW
AIFL Double Nickase Plasmid (m)
sc-428262-NICmouseGene KnockoutPuromycinNEW
AIFL Double Nickase Plasmid (m2)
sc-428262-NIC-2mouseGene KnockoutPuromycinNEW

AIF CRISPR Activation Plasmids include:

PRODUCT NAMECAT. #SPECIESAPPLICATIONSMARKERCITATIONS
AIF CRISPR Activation Plasmid (h)
sc-400370-ACThumanGene ActivationZeo, Blast, HygroNEW
AIF CRISPR Activation Plasmid (h2)
sc-400370-ACT-2humanGene ActivationZeo, Blast, HygroNEW
AIF Lentiviral Activation Particles (h)
sc-400370-LAChumanGene ActivationZeo, Blast, HygroNEW
AIF Lentiviral Activation Particles (h2)
sc-400370-LAC-2humanGene ActivationZeo, Blast, HygroNEW
AIFL CRISPR Activation Plasmid (h)
sc-414674-ACThumanGene ActivationZeo, Blast, HygroNEW
AIFL CRISPR Activation Plasmid (h2)
sc-414674-ACT-2humanGene ActivationZeo, Blast, HygroNEW
AIFL Lentiviral Activation Particles (h)
sc-414674-LAChumanGene ActivationZeo, Blast, HygroNEW
AIFL Lentiviral Activation Particles (h2)
sc-414674-LAC-2humanGene ActivationZeo, Blast, HygroNEW
AIF CRISPR Activation Plasmid (m)
sc-424143-ACTmouseGene ActivationZeo, Blast, HygroNEW
AIF CRISPR Activation Plasmid (m2)
sc-424143-ACT-2mouseGene ActivationZeo, Blast, HygroNEW
AIF Lentiviral Activation Particles (m)
sc-424143-LACmouseGene ActivationZeo, Blast, HygroNEW
AIF Lentiviral Activation Particles (m2)
sc-424143-LAC-2mouseGene ActivationZeo, Blast, HygroNEW
AIFL CRISPR Activation Plasmid (m)
sc-428262-ACTmouseGene ActivationZeo, Blast, HygroNEW
AIFL CRISPR Activation Plasmid (m2)
sc-428262-ACT-2mouseGene ActivationZeo, Blast, HygroNEW
AIFL Lentiviral Activation Particles (m)
sc-428262-LACmouseGene ActivationZeo, Blast, HygroNEW
AIFL Lentiviral Activation Particles (m2)
sc-428262-LAC-2mouseGene ActivationZeo, Blast, HygroNEW

AIF siRNA, shRNA Plasmid and shRNA Lentiviral Particles gene silencers include:

PRODUCT NAMECAT. #SPECIESAPPLICATIONSMARKERCITATIONS
AIF siRNA (h)
sc-29193humanGene SilencingN/A5
AIF shRNA Plasmid (h)
sc-29193-SHhumanGene SilencingPuromycin
AIF shRNA (h) Lentiviral Particles
sc-29193-VhumanGene SilencingPuromycin
AIF siRNA (m)
sc-29194mouseGene SilencingN/A2
AIF shRNA Plasmid (m)
sc-29194-SHmouseGene SilencingPuromycin
AIF shRNA (m) Lentiviral Particles
sc-29194-VmouseGene SilencingPuromycin
AIF siRNA (h2)
sc-44243humanGene SilencingN/A
AIF shRNA Plasmid (h2)
sc-44243-SHhumanGene SilencingPuromycin
AIF shRNA (h2) Lentiviral Particles
sc-44243-VhumanGene SilencingPuromycin
AIFL siRNA (h)
sc-72467humanGene SilencingN/A
AIFL shRNA Plasmid (h)
sc-72467-SHhumanGene SilencingPuromycin
AIFL shRNA (h) Lentiviral Particles
sc-72467-VhumanGene SilencingPuromycin
AIFL siRNA (m)
sc-140965mouseGene SilencingN/A
AIFL shRNA Plasmid (m)
sc-140965-SHmouseGene SilencingPuromycin
AIFL shRNA (m) Lentiviral Particles
sc-140965-VmouseGene SilencingPuromycin

A key event in the apoptotic process is the opening of the mitochondrial permeability transition pore, an event that is regulated by Bcl-2 family proteins, resulting in the release of several proteins from the mitochondrial intermembrane space. Several of these proteins participate in apoptosis, including cytochrome c, procaspases-2, -3 and -9, and AIF (apoptosis-inducing factor). AIF was shown to cause DNA fragmentation and chromatin condensation, and to induce the release of cytochrome c and caspase-9 from mitochondria. Bcl-2 overexpression was shown to prevent the release of AIF from mitochondria, but not to block its apoptogenic activity.