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AIF Antibodies

Santa Cruz Biotechnology, Inc. offers a broad range of AIF antibodies. Select AIF antibodies from several monoclonal and/or polyclonal AIF antibodies listed below. View detailed AIF antibody specifications by linking to the specific product blocks. Select appropriate AIF antibodies for your research by isotype, epitope, applications and species reactivity. AIF gene silencer products in siRNA, shRNA Plasmid, shRNA Lentiviral Particle and CRISPR/Cas9 Knockout Plasmid formats are also available as well as CRISPR/dCas9 Activation Plasmids for gene activation.

Introducing HOVERcruz™,

a unique system for rapid identification of AIF Antibodies. Hover over product names in the table to see representative data for each product.

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Our live chat system is available to answer your product and ordering questions.

Also see additional AIF Antibodies including, AIFL

PRODUCT NAMECAT. #ISOTYPEEPITOPEAPPLICATIONSSPECIESCITATIONSRATING
AIF (B-9)sc-55519mouse IgG2a1-300 (h)WB, IP, IF, IHC(P), ELISAm, h5
AIF (D-20)sc-9416goat IgGC-terminal (m)WB, IP, IF, IHC(P), ELISAm, r, h, e, c, b, p, a49
AIF (E-1)sc-13116mouse IgG2b1-300 (h) WB, IP, IF, IHC(P), FCM, ELISAm, r, h75
AIF (E-11)sc-390619mouse IgM586-612 (m)WB, IP, IF, ELISAm, r, h, e, c, b, pNEW
AIF (N-19)sc-9417goat IgGN-terminal (h)WB, IP, IF, IHC(P), ELISAh, e, c, b, p > m6
AIF (H-300)sc-5586rabbit IgG1-300 (h)WB, IP, IF, ELISAm, r, h, e, c, b, p38
AIFL (A-9)sc-376570mouse IgG11-300 (h)WB, IP, IF, ELISAhuman
AIFL (H-300)sc-292446rabbit IgG1-300 (h)WB, IP, IF, ELISAm, r, h
AIFL (K-14)sc-86277rabbit IgGInternal (h)WB, IP, IF, ELISAm, r, h, e, c, b, p
AIFL (Q-14)sc-86279rabbit IgGInternal (h)WB, IP, IF, ELISAm, r, h, e, b, p

AIF CRISPR Knockout and HDR Plasmids include:

PRODUCT NAMECAT. #SPECIESAPPLICATIONSCITATIONSRATING
AIF CRISPR/Cas9 KO Plasmid (h)sc-400370humanGene KnockoutNEWNot Yet Rated
AIF HDR Plasmid (h)sc-400370-HDRhumanHomology Directed RepairNEWNot Yet Rated
AIFL CRISPR/Cas9 KO Plasmid (h)sc-414674humanGene KnockoutNEWNot Yet Rated
AIFL HDR Plasmid (h)sc-414674-HDRhumanHomology Directed RepairNEWNot Yet Rated
AIF CRISPR/Cas9 KO Plasmid (m)sc-424143mouseGene KnockoutNEWNot Yet Rated
AIF HDR Plasmid (m)sc-424143-HDRmouseHomology Directed RepairNEWNot Yet Rated
AIFL CRISPR/Cas9 KO Plasmid (m)sc-428262mouseGene KnockoutNEWNot Yet Rated
AIFL HDR Plasmid (m)sc-428262-HDRmouseHomology Directed RepairNEWNot Yet Rated

AIF CRISPR Activation Plasmids include:

PRODUCT NAMECAT. #SPECIESAPPLICATIONSCITATIONSRATING
AIF CRISPR Activation Plasmid (h)sc-400370-ACThumanGene ActivationNEWNot Yet Rated
AIFL CRISPR Activation Plasmid (h)sc-414674-ACThumanGene ActivationNEWNot Yet Rated
AIF CRISPR Activation Plasmid (m)sc-424143-ACTmouseGene ActivationNEWNot Yet Rated
AIFL CRISPR Activation Plasmid (m)sc-428262-ACTmouseGene ActivationNEWNot Yet Rated

AIF siRNA, shRNA Plasmid and shRNA Lentiviral Particles gene silencers include:

PRODUCT NAMECAT. #SPECIESAPPLICATIONSCITATIONSRATING
AIF siRNA (h)sc-29193humanGene Silencing5
AIF shRNA Plasmid (h)sc-29193-SHhumanGene Silencing
AIF shRNA (h) Lentiviral Particlessc-29193-VhumanGene Silencing
AIF siRNA (m)sc-29194mouseGene Silencing2
AIF shRNA Plasmid (m)sc-29194-SHmouseGene Silencing
AIF shRNA (m) Lentiviral Particlessc-29194-VmouseGene Silencing
AIF siRNA (h2)sc-44243humanGene Silencing
AIF shRNA Plasmid (h2)sc-44243-SHhumanGene Silencing
AIF shRNA (h2) Lentiviral Particlessc-44243-VhumanGene Silencing
AIFL siRNA (h)sc-72467humanGene SilencingNot Yet Rated
AIFL shRNA Plasmid (h)sc-72467-SHhumanGene SilencingNot Yet Rated
AIFL shRNA (h) Lentiviral Particlessc-72467-VhumanGene SilencingNot Yet Rated
AIFL siRNA (m)sc-140965mouseGene SilencingNot Yet Rated
AIFL shRNA Plasmid (m)sc-140965-SHmouseGene SilencingNot Yet Rated
AIFL shRNA (m) Lentiviral Particlessc-140965-VmouseGene SilencingNot Yet Rated

A key event in the apoptotic process is the opening of the mitochondrial permeability transition pore, an event that is regulated by Bcl-2 family proteins, resulting in the release of several proteins from the mitochondrial intermembrane space. Several of these proteins participate in apoptosis, including cytochrome c, procaspases-2, -3 and -9, and AIF (apoptosis-inducing factor). AIF was shown to cause DNA fragmentation and chromatin condensation, and to induce the release of cytochrome c and caspase-9 from mitochondria. Bcl-2 overexpression was shown to prevent the release of AIF from mitochondria, but not to block its apoptogenic activity.