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AGRP AntibodiesSanta Cruz Biotechnology, Inc. offers a broad range of AGRP antibodies. Select AGRP antibodies from several monoclonal and/or polyclonal AGRP antibodies listed below. View detailed AGRP antibody specifications by linking to the specific product blocks. Select appropriate AGRP antibodies for your research by isotype, epitope, applications and species reactivity. AGRP gene silencer products in siRNA, shRNA Plasmid and shRNA Lentiviral Particle formats are also available. Introducing HOVERcruz™,a unique system for rapid identification of AGRP Antibodies. Hover over product names in the table to see representative data for each product.Live chat is now available! (click here)Our live chat system is available to answer your product and ordering questions.
AGRP siRNA, shRNA Plasmid and shRNA Lentiviral Particles gene silencers include:
ASP (agouti signaling protein or agouti switch protein) is a paracrine signaling molecule that causes hair follicle melanocytes to synthesize pheomelanin, a yellow pigment, instead of the black or brown pigment eumelanin. Consequently, agouti mice produce hairs with a subapical yellow band on an otherwise black or brown background when expressed during the midportion of hair growth. ASP is a 132-amino acid protein with a consensus signal peptide, indicating that the protein is probably secreted and is normally expressed in neonatal skin. The gene which encodes for ASP maps to human chromosome 20q11.2. AGRP (agouti-related protein) is a potent, selective antagonist of MC3R and MC4R. AGRP normally regulates body weight via central melanocortin receptors, analogous to the relation between agouti and MC1R for regulation of pigmentation. AGRP is expressed primarily in the adrenal gland, subthalamic nucleus and hypothalamus, with a lower level of expression occurring in testis, lung and kidney. The gene which encodes for AGRP maps to human chromosome 16q22. |
