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- goat polyclonal IgG, 200µg/ml
- epitope mapping within an internal region of UBA5 of human origin
- recommended for detection of UBA5 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
- blocking peptide, sc-99702 P
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Informacoes sobre ordens
Produtos Auxiliares Recomendados
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| Especies |
nome do gene |
Identificacao do gene |
Localizacao do cromossomo |
Numero de acesso de isoformas de RNA mensageiro |
Numero de acesso de proteina |
OMIM&trande; Numero |
| Humano |
UBE1DC1 |
79876 |
3q22.1 |
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Q9GZZ9
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610552 |
| camundongo |
Uba5 |
66663 |
9 F1 |
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Q8VE47
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N/A |
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UBA5 Background Information
Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). UBA5 (Ubiquitin-activating enzyme 5), also known as UBE1DC1 or THIFP1, is a 404 amino acid protein that belongs to the E1-like ubiquitin-activating enzyme family. Existing as two alternatively spliced isoforms, UBA5 forms a high-energy thioester bond with UFM1 (ubiquitin-fold modifier 1), a protein involved in post-translational modification. Via formation of a thioester bond, UBA5 activates UFM1 function and may, thus, play a role in the regulation of post-translational modification events. |
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UBA5 (E-19)
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UBA5 (E-19): sc-99702. Western blot analysis of UBA5 expression in non-transfected: sc-117752 (A) and human UBA5 transfected: sc-111232 (B) 293T whole cell lysates. UBA5 (E-19): sc-99702. Western blot analysis of UBA5 expression in non-transfected: sc-117752 (A) and mouse UBA5 transfected: sc-124393 (B) 293T whole cell lysates. |
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