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- rabbit polyclonal IgG, 200µg/ml
- epitope mapping near the N-terminus of β-SNAP of human origin
- recommended for detection of β-SNAP of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including canine, bovine, porcine and avian
- blocking peptide, sc-98026 P
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Informacoes sobre ordens
Produtos Auxiliares Recomendados
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| Especies |
nome do gene |
Identificacao do gene |
Localizacao do cromossomo |
Numero de acesso de isoformas de RNA mensageiro |
Numero de acesso de proteina |
OMIM&trande; Numero |
| Humano |
NAPB |
63908 |
20p11.21 |
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Q9H115
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611270 |
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β-SNAP Background Information
Syntaxins were originally thought to be docking proteins, but have more recently been categorized as anchoring proteins that anchor themselves to the cytoplasmic surfaces of cellular membranes. Syntaxins have been shown to bind to various proteins involved in exocytosis, including VAMPs (vesicle-associated membrane proteins), NSF (N-ethylmaleimide-sensitive factor), SNAP 25 (synaptosomal-associated protein of 25kDa), SNAPs (soluble NSF attachment proteins) and synaptotagmin. VAMPs (also designated synaptobrevins), including VAMP-1 and VAMP-2, and synaptotagmin, a protein that may function as an inhibitor of exocytosis, are vesicular proteins. SNAPs, including å-SNAP, ∫-SNAP and ©-SNAP, are cytoplasmic proteins that bind to a membrane receptor complex composed of VAMP, SNAP 25 and syntaxin. While å-SNAP and ©-SNAP, are found in a wide range of tissues, ∫-SNAP is expressed only in the brain. The gene encoding ∫-SNAP is localized to chromosome 20p11.21. |
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β-SNAP (E-13)
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β-SNAP (E-13): sc-98026. Western blot analysis of β-SNAP expression in non-transfected: sc-117752 (A) and mouse β-SNAP transfected: sc-127560 (B) 293T whole cell lysates. |
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