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- goat polyclonal IgG, 200µg/ml
- epitope mapping within a C-terminal cytoplasmic domain of GODZ of human origin
- recommended for detection of GODZ of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
- blocking peptide, sc-79960 P
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Informacoes sobre ordens
Produtos Auxiliares Recomendados
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| Especies |
nome do gene |
Identificacao do gene |
Localizacao do cromossomo |
Numero de acesso de isoformas de RNA mensageiro |
Numero de acesso de proteina |
OMIM&trande; Numero |
| Humano |
ZDHHC3 |
51304 |
3p21.31 |
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Q9NYG2
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n/a |
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GODZ Background Information
Golgi-specific DHHC (Asp-His-His-Cys) zinc finger protein (GODZ), also known as, Palmitoyltransferase ZDHHC3 or Zinc finger protein 373, is a 327 amino acid protein member of the DHHC palmitoyltransferase family. Localized to the Golgi apparatus membrane, GODZ contains one DHHC-type zinc finger, which is necessary for its palmitoyltransferase activity. GODZ has been implicated in the palmitoylation and regulated trafficking of diverse substrates that function various inhibitory and excitatory synapses. Specifically, it palmitoylates the gamma subunit 2 of GABA(A) receptors, which leads to normal synaptic GABAergic inhibitory function. GODZ also palmitoylates glutamate receptors GRIA1 and GRIA2, which leads to their retention in Golgi. Two isoforms of GODZ exist as a result of alternative splicing events. |
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GODZ (C-13)
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GODZ (C-13): sc-79960. Western blot analysis of GODZ expression in SK-N-MC (A), HeLa (B) and U-87 MG (C) whole cell lysates.
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