NAT-5 (E-17) Anticorpo: sc-65145

NAT-5 Background Information
Acetyltransferases and deacetylases are protein groups most often associated with oncogenesis and cell cycle regulation. NAT-5 (N-acetyltransferase 5) is an intracellular protein involved in N-acetylation, particularly the acetylation of histones. NAT-5 is a component of the ARD1-NAT-1 (human arrest defective 1 - N-acetyltransferase) complex, which acetylates the alpha-amino groups of proteins during translation. NAT-5 contains an enzymatic acetyltransferase domain, which makes it an active component of the complex. ARD1 and NAT-1 have both shown upregulation in certain cancers and may facilitate the metastasis of papillary thyroid carcinomas.