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- goat polyclonal IgG, 200µg/ml
- epitope mapping at the N-terminus of MRP-L28 of human origin
- recommended for detection of MRP-L28 of human origin by WB, IP, IF and ELISA; also reactive with additional species, including canine, bovine and porcine
- blocking peptide, sc-55685 P
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Informacoes sobre ordens
Produtos Auxiliares Recomendados
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| Especies |
nome do gene |
Identificacao do gene |
Localizacao do cromossomo |
Numero de acesso de isoformas de RNA mensageiro |
Numero de acesso de proteina |
OMIM&trande; Numero |
| Humano |
MRPL28 |
10573 |
16p13.3 |
NM_006428 |
Q13084
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604853 |
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MRP-L28 Background Information
MRP-L28 (39S ribosomal protein L28, melanoma-associated antigen recognized by T lymphocytes) is a mitochondrial protein that belongs to the ribosomal protein L28P family. MRP-L28 potentially represents an important therapeutic reagent for HLA-A24 (A24) patients as this antigen is recognized by tumor-infiltrating lymphocyte (TIL) 1290, which targets the A24 serotype. HLA-A24 (A24) is an HLA-A serotype that identifies the more common HLA-A24 gene products. A24 is a split antigen that is also recognized by the A9 broad antigen type and the similar A23 types. A24 is common in Austronesia and has one of the highest A allele frequencies for a number of peoples, including Papua New Guineans, indigeonous Taiwanese (eastern tribals), Yupik and Greenland Eskimos. MRP-L28 is found in a variety of normal tissues including spleen, testis, thymus, liver, kidney, brain, adrenal, lung and retinal tissue.
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MRP-L28 (N-18)
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MRP-L28 (N-18): sc-55685. Western blot analysis of MRP-L28 expression in Hs 294T whole cell lysate.
MRP-L28 (N-18): sc-55685. Western blot analysis of MRP-L28 expression in non-transfected: sc-110760 (A) and human MRP-L28 transfected: sc-110593 (B) 293 whole cell lysates. MRP-L28 (N-18): sc-55685. Western blot analysis of MRP-L28 expression in HeLa whole cell lysate.
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