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- goat polyclonal IgG, 200µg/ml
- epitope mapping at the C-terminus of IDH3G of human origin
- recommended for detection of IDH3G of human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
- blocking peptide, sc-55677 P
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Informacoes sobre ordens
Produtos Auxiliares Recomendados
(clique na sua escolha)
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| Especies |
nome do gene |
Identificacao do gene |
Localizacao do cromossomo |
Numero de acesso de isoformas de RNA mensageiro |
Numero de acesso de proteina |
OMIM&trande; Numero |
| Humano |
IDH3G |
3421 |
Xq28 |
NM_004135, NM_174869 |
P51553
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300089 |
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IDH3G Background Information
IDH3G (Isocitrate dehydrogenase [NAD] subunit g (mitochondrial), NAD(+)-specific ICDH) is a 393 amino acid protein encoded by the human gene IDH3G. IDH3G belongs to the isocitrate and isopropylmalate dehydrogenases family and can bind one magnesium or manganese ion per subunit. It is usually found in the mitochondrion as a heterooligomer of subunits a, b, and g in the apparent ratio of 2:1:1. Human NAD-dependent isocitrate dehydrogenase (IDH) is allosterically activated by ADP by lowering the Km for isocitrate. NAD-dependent isocitrate dehydrogenase is a tricarboxylic acid cycle enzyme that produces 2-oxoglutarate, an organic acid required by the glutamine synthetase/glutamate synthase cycle to assimilate ammonium. |
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IDH3G (C-19)
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IDH3G (C-19): sc-55677. Western blot analysis of IDH3G expression in HT-1080 (A), RD (B), A-673 (C), MCF7 (D) and SK-BR-3 (E) whole cell lysates.
IDH3G (C-19): sc-55677. Western blot analysis of IDH3G expression in non-transfected 293: sc-110760 (A), human IDH3G transfected 293: sc-110789 (B), SK-BR-3 (C), HT-1080 (D), HeLa (E) and MCF7 (F) whole cell lysates. IDH3G (C-19): sc-55677. Western blot analysis of IDH3G expression in MCF7 (A), SK-BR-3 (B), HeLa (C) and A-673 (D) whole cell lysates.
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