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- goat polyclonal IgG, 200µg/ml
- epitope mapping near the C-terminus of ICK of mouse origin
- recommended for detection of ICK of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
- blocking peptide, sc-48020 P
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Informacoes sobre ordens
Produtos Auxiliares Recomendados
(clique na sua escolha)
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| Especies |
nome do gene |
Identificacao do gene |
Localizacao do cromossomo |
Numero de acesso de isoformas de RNA mensageiro |
Numero de acesso de proteina |
OMIM&trande; Numero |
| Humano |
ICK |
22858 |
6p12.1 |
NM_014920, NM_016513 |
Q9UPZ9
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n/a |
| camundongo |
Ick |
56542 |
9 E1 |
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Q9JKV2
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N/A |
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ICK Background Information
Intestinal cell kinase (ICK), also designated MRK, LCK2, KIAA0936 and MGC46090, is a nuclear Cdc2-related kinase. ICK shares nearly identical N-terminal catalytic domains with male germ cell-associated kinase (MAK), however the C-terminal noncatalytic domain of intestinal cell kinase diverges from that of MAK. The catalytic domain of ICK is also related to mitogen-activated protein kinases (MAPKs) and harbors a corresponding TDY motif, the dual phosphorylation of which activates ICK. The phosphorylation of Tyr 159 in the TDY motif requires ICK autokinase activity, but confers only basal kinase activity; full activation of the protein requires additional phosphorylation of Thr 157 in the TDY motif. |
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ICK (C-19)
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ICK (C-19): sc-48020. Western blot analysis of ICK expression in NIH/3T3 (A) and SW480 (B) nuclear extracts.
ICK (C-19): sc-48020. Western blot analysis of ICK expression in NIH/3T3 whole cell lysate.
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