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- goat polyclonal IgG, 200 µg/ml
- epitope mapping within a cytoplasmic domain of GABAA Rγ3 of human origin
- recommended for detection of GABAA Rγ3 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including canine, bovine and porcine
- blocking peptide, sc-31434 P
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Informacoes sobre ordens
Produtos Auxiliares Recomendados
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| Especies |
nome do gene |
Identificacao do gene |
Localizacao do cromossomo |
Numero de acesso de isoformas de RNA mensageiro |
Numero de acesso de proteina |
OMIM&trande; Numero |
| Humano |
GABRG3 |
2567 |
15q12 |
NM_033223 |
Q99928
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600233 |
| camundongo |
Gabrg3 |
14407 |
7 C |
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P27681
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N/A |
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GABAA Rγ3 Background Information
GAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl- conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. Members of the GABAA receptor family include GABAA Rå1-6, GABAA R ∫1-3, GABAA R©1-3, GABAA R∂, GABAA Ré, GABAA Rρ1 and GABAA Rρ2. The GABAB family is composed of GABAB R1å and GABAB R1∫. GABA transporters have also been identified and include GABA T-1, GABA T-2 and GABA T-3 (also designated GAT-1, -2, and -3). The GABA transporters function to terminate GABA action. |
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GABAA Rγ3 (P-19)
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GABAA Rg3 (P-19): sc-31434. Western blot analysis of GABAA Rγ3 expression in mouse testis tissue extract.
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