Date published: 2026-8-20

1-800-457-3801

SCBT Portrait Logo
Seach Input

p-MEK-1 Antibody (47.Ser 222): sc-136542

3.2(5)
Write a reviewAsk a question

Datasheets
  • p-MEK-1 Antibody (47.Ser 222) is a mouse monoclonal IgA, cited in 4 publications, provided at 200 µg/ml
  • raised against a short amino acid sequence containing phosphorylated Ser 222 of MEK-1 of human origin
  • recommended for detection of Ser 222 phosphorylated MEK-1 and Ser 222 phosphorylated MEK-2 of mouse, rat and human origin by WB, IP and ELISA
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for p-MEK-1 Antibody (47.Ser 222). This work is in progress.
Gene Editing Promo Banner

QUICK LINKS

SEE ALSO...

p-MEK-1 Antibody (47.Ser 222) is a mouse monoclonal IgA antibody that detects p-MEK-1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). p-MEK-1 (47.Ser 222) antibody is available in a non-conjugated form and specifically recognizes Ser 222 phosphorylated MEK-1 and MEK-2, which are critical components of the MAP kinase signaling pathway. MEK-1, also known as MAP2K1, plays a vital role in cellular signaling by acting as a dual-specificity kinase that phosphorylates both threonine and tyrosine residues on downstream targets, particularly extracellular signal-regulated kinases (ERKs). This phosphorylation activates ERKs, which drive various cellular processes, including proliferation, differentiation, and survival. Precise regulation of MEK-1 activity through phosphorylation is crucial, as dysregulation can lead to oncogenic transformations and contribute to various diseases, including cancer. Understanding p-MEK-1 function and regulation is important for developing targeted therapies and advancing knowledge of signal transduction mechanisms.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

p-MEK-1 Antibody (47.Ser 222)

sc-136542
200 µg/ml
$322.00