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- rabbit polyclonal IgG, 100µg/ml
- raised against SAP 30BP of human origin
- recommended for detection of SAP 30BP of mouse, rat, human and canine origin by WB, IP and ELISA
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Informacoes sobre ordens
Produtos Auxiliares Recomendados
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| Especies |
nome do gene |
Identificacao do gene |
Localizacao do cromossomo |
Numero de acesso de isoformas de RNA mensageiro |
Numero de acesso de proteina |
OMIM&trande; Numero |
| Humano |
SAP30BP |
29115 |
17q25.1 |
NM_013260 |
Q9UHR5
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610218 |
| camundongo |
Sap30bp |
57230 |
11 E2 |
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Q02614
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N/A |
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SAP 30BP Background Information
SAP 30BP (SAP 30 binding protein), also known as HTRG, HTRP or HCNGP, is a 308 amino acid protein that belongs to the HCNGP family and is believed to function as a transcription regulator. Expressed in brain, liver, spleen, kidney, lung and heart, SAP 30BP localizes to the nucleus and is induced in fibroblasts by binding of HSV-1 (herpes simplex virus 1). In the nucleus, SAP 30BP interacts with SAP 30, a component of the histone deacetylase complex that also contains mSin3A, HDAC1, HDAC2, RbAp48, RbAp46 and SAP 18. Via this interaction, SAP 30BP is thought to play a role in the regulation of genes related to cell survival. In addition, SAP 30BP is capable of inducing cell death, suggesting that it functions in cellular corepression of transcription and inhibition of cell survival. |
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SAP 30BP (S-25)
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SAP 30BP (S-25): sc-102103. Western blot analysis of SAP 30BP expression in fetal muscle tissue extract.
SAP 30BP (S-25): sc-102103. Western blot analysis of SAP 30BP expression in non-transfected: sc-117752 (A) and human SAP 30BP transfected: sc-117236 (B) 293T whole cell lysates. |
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