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Stat1α p91 Antibody (C-24): sc-345

 |  Datasheet

(Based on data analysis)

  • Stat1α p91 Antibody (C-24) is a rabbit polyclonal IgG provided at 200 µg/ml
  • epitope mapping at the C-terminus of Stat1α p91 of human origin
  • recommended for detection of Stat1α p91 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine and canine equine and canine
  • blocking peptide, sc-345 P
  • TransCruz reagent for Gel Supershift and ChIP applications, sc-345 X, 200 µg/0.1 ml
  • See 51 citations for Stat1α p91 Antibody (C-24)
 

See additional Stat Antibodies including Stat, Stat1, Stat2, Stat3, Stat4, Stat5 and Stat6.

Also see chemical Stat1 Inhibitors for functional analysis of cellular responses to Stat1.


Ordering InformationProduct CitationsGene Info
Recommended Support Products:
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WB   IP   IF   Gel Shift   ChIP   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
Stat1α p91 Antibody (C-24) sc-345 200 µg/ml $279
Stat1α p91 (C-24) P sc-345 P
(peptide)
100 µg/0.5 ml $61
Stat1α p91 Antibody (C-24) X sc-345 X 200 µg/0.1 ml $279
 CRISPR/Cas9 KO and HDR Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Stat1 p84/p91 CRISPR/Cas9 KO Plasmid (m) sc-423174 20 µg $345
Stat1 p84/p91 HDR Plasmid (m) sc-423174-HDR 20 µg $385
Stat1 p84/p91 CRISPR/Cas9 KO Plasmid (h) sc-400086 20 µg $345
Stat1 p84/p91 HDR Plasmid (h) sc-400086-HDR 20 µg $385
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Stat1 p84/p91 siRNA (h) sc-44123 10 µM $258
Stat1 p84/p91 siRNA (m) sc-44124 10 µM $258
Stat1 p84/p91 (h)-PR sc-44123-PR 10 µM, 20 µl $23
Stat1 p84/p91 (m)-PR sc-44124-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Stat1 p84/p91 shRNA Plasmid (h) sc-44123-SH 20 µg $520
Stat1 p84/p91 shRNA Plasmid (m) sc-44124-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Stat1 p84/p91 shRNA (h) Lentiviral Particles sc-44123-V 200 µl $625
Stat1 p84/p91 shRNA (m) Lentiviral Particles sc-44124-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
HeLa + PMA nuclear extract sc-2121 250 µg/0.05 ml $143
HeLa + IFN-γ Cell Lysate sc-2222 500 µg/200 µl $104
A-431 + PMA nuclear extract sc-2123 250 µg/0.05 ml $143
NIH/3T3 nuclear extract sc-2138 250 µg/0.05 ml $143
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human STAT1 6772 2q32.2 NM_007315, NM_139266 P42224
600555
Mouse Stat1 20846 1 C1.1 P42225
N/A
 


Membrane receptor signaling by various ligands, including interferons and growth hormones such as EGF, induces activation of JAK kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN-α and form a heterodimer which is part of the ISGF3 transcription factor complex. Although early reports indicate Stat3 activation by EGF and IL-6, it has been shown that Stat3β appears to be activated by both while Stat3α is activated by EGF, but not by IL-6. Highest expression of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 has been shown to be activated by Prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways.

Stat1α p91 Antibody (C-24) Product Citations
See how others have used Stat1α p91 Antibody (C-24) and or Stat1α p91 Antibody (C-24) conjugates.


51 total citations
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Stat1α p91 Antibody (C-24) Data
Click on image to enlarge
Western blot analysis of Stat1a p91 and Stat1b p84 expression in nuclear extracts of phorbol ester-treated HeLa (A,D), A-431 (B,E) and K-562 (C,F) cells. Antibodies include Stat1a p91 (C-24): sc-345 (AC) and Stat1 p84/p91 (E-23): sc-346 (DF).
Stat1α p91 (C-24): sc-345. Western blot analysis of Stat1α p91 If expression in HeLa whole cell lysate.
Stat1α p91 (C-24): sc-345. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic and nuclear localization.
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