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January 2016 Investigator Award Winner
Nesrine Abboud
We are pleased to announce Nesrine Abboud as the winner of the January 2016 Investigator Award for the following publication:
Abboud N, Moore-Morris T, Hiriart E, Yang H, Bezerra H, Gualazzi MG, Stefanovic S, Guénantin AC, Evans SM, Pucéat M. A cohesin-OCT4 complex mediates Sox enhancers to prime an early embryonic lineage. Nat Commun. 2015 Apr 8;6:6749. PMID: 25851587
As the January 2016 Investigator Award winner, Nesrine Abboud will receive 5000 Cruz Credits™ to be used toward future product purchases.
SCBT Investigator Award Winners
January 2016
Nesrine Abboud

Abboud N, Moore-Morris T, Hiriart E, Yang H, Bezerra H, Gualazzi MG, Stefanovic S, Guénantin AC, Evans SM, Pucéat M. A cohesin-OCT4 complex mediates Sox enhancers to prime an early embryonic lineage. Nat Commun. 2015 Apr 8;6:6749. PMID: 25851587
July 2015
Tobias Wagner

Wagner T, Kiweler N, Wolff K, Knauer SK, Brandl A, Hemmerich P, Dannenberg JH, Heinzel T, Schneider G, Krämer OH. Sumoylation of HDAC2 promotes NF-κB-dependent gene expression. Oncotarget. 2015 Mar 30;6(9):7123-35. PubMed PMID: 25704882; PubMed Central PMCID: PMC4466673.
January 2015
Norman Ertych

Ertych N, Stolz A, Stenzinger A, Weichert W, Kaulfuß S, Burfeind P, Aigner A, Wordeman L, Bastians H. Increased microtubule assembly rates influence chromosomal instability in colorectal cancer cells. Nat Cell Biol. 2014 Aug;16(8):779-91. PubMed PMID: 24976383.
July 2014
Michelino Di Rosa

Di Rosa M, Tibullo D, Vecchio M, Nunnari G, Saccone S, Di Raimondo F, Malaguarnera L. Determination of chitinases family during osteoclastogenesis. Bone. 2014 Apr;61:55-63.PMID: 24440516.
January 2014
Daniel Martinez Molina

Daniel Martinez Molina, Rozbeh Jafari, Marina Ignatushchenko, Takahiro Seki, E. Andreas Larsson, Chen Dan, Lekshmy Sreekumar, Yihai Cao, Pär Nordlund. Monitoring Drug Target Engagement in Cells and Tissues Using the Cellular Thermal Shift Assay. Science. 2013 July 5;341(6141):84-87. PMID: 23828940
July 2013
Simona Morone

Morone S, Lo-Buono N, Parrotta R, Giacomino A, Nacci G, Brusco A, Larionov A, Ostano P, Mello-Grand M, Chiorino G, Ortolan E, Funaro A. Overexpression of CD157 contributes to epithelial ovarian cancer progression by promoting mesenchymal differentiation. PLoS One. 2012;7(8):e43649. PMID: 22916288
January 2013
Pol Margalef

Margalef P, Fernández-Majada V, Villanueva A, Garcia-Carbonell R, Iglesias M, López L, Martínez-Iniesta .M, Villà-Freixa J, Mulero MC, Andreu M, Torres F, Mayo MW, Bigas A, Espinosa L. A Truncated Form of IKKα Is Responsible for Specific Nuclear IKK Activity in Colorectal Cancer. Cell Reports. 2012 October 25; 2(4):840-854. PMID: 23041317
July 2012
Maria Rosaria Amoroso

Amoroso MR, Matassa DS, Laudiero G, Egorova AV, Polishchuk RS, Maddalena F, Piscazzi A, Paladino S, Sarnataro D, Garbi C, Landriscina M, Esposito F. TRAP1 and the proteasome regulatory particle TBP7/Rpt3 interact in the endoplasmic reticulum and control cellular ubiquitination of specific mitochondrial proteins. Cell Death Differ. 2012 19(4):592-604. PMID 21979464.
January 2012
Bilal Hafeez

Bilal Bin Hafeez, Weixiong Zhong, Jamey Weichert, Nancy E. Dreckschmidt, Mohammad Sarwar Jamal, Ajit K. Verma. Genetic ablation of PKC epsilon inhibits prostate cancer development and metastasis in transgenic mouse model of prostate adenocarcinoma. Cancer Res. 2011 71(6):2318-2327. PMID 21406403.
July 2011
Chih-Hsin Tang

Chih-Hsin Tang, Cheng-Fong Chen, Wei-Ming Chen, Yi-Chin Fong. IL-6 Increases MMP-13 Expression and Motility in Human Chondrosarcoma Cells. J Biol Chem. 2011 286(13):11056-66. PMID: 21278254
January 2011
Prerna Kumar

Prerna Kumar, Renu Garg, Gevoni Bolden, Kailash N. Pandey. Interactive roles of Ets-1, Sp1, and acetylated histones in the retinoic acid-dependent activation of guanylyl cyclase/atrial natriuretic peptide receptor-A gene transcription. J Biol Chem. 2010 285(48):37521-37530. PMID: 20864529
July 2010
Barbara Bellei

Barbara Bellei, Vittoria Maresca, Enrica Flori, Angela Pitisci, Lionel Larue, Mauro Picardo. p38 regulates pigmentation via proteasomal degradation of tyrosinase. J Biol Chem. 2010 Mar 5;285(10):7288-99. PMID 20053998
January 2010
Pan-Yue Deng

Pan-Yue Deng, Zhaoyang Xiao, Chuanxiu Yang, Lalida Rojanathammanee, Laurel Grisanti, John Watt, Jonathan D. Geiger, Rugao Liu, James E. Porter and Saobo Lei. GABAB Receptor Activation Inhibits Neuronal Excitability and Spatial Learning in the Entorhinal Cortex by Activating TREK-2 K+ Channels. Neuron 2009 63(2):230-243. PMID: 19640481
July 2009
Richard Tomasini

Richard Tomasini, Katsuya Tsuchihara, Chiharu Tsuda, Suzanne K. Lau, Margareta Wilhelm, Alessandro Ruffini, Ming-sound Tsao, Juan L. Iovanna, Andrea Jurisicova, Gerry Melino, and Tak W. Mak. TAp73 regulates the spindle assembly checkpoint by modulating BubR1 activity. Proc Natl Acad Sci U S A. 2009 106(3):797-802. PMID: 19139399
January 2009
Ning Ding

Ning Ding, Haiying Zhou, Pierre-Olivier Esteve, Hang Gyeong Chin, Seokjoong Kim, Xuan Xu, Sumy M. Joseph, Michael J. Friez, Charles E. Schwartz, Sriharsa Pradhan and Thomas G. Boyer. Mediator links epigenetic silencing of neuronal gene expression with x-linked mental retardation. Molecular Cell. 2008 31:347-359. PMID: 18691967
July 2008
Melissa R. Junttila

Junttila MR, Puustinen P, Niemelä M, Ahola R, Arnold H, Böttzauw T, Ala-aho R, Nielsen C, Ivaska J, Taya Y, Lu SL, Lin S, Chan EK, Wang XJ, Grènman R, Kast J, Kallunki T, Sears R, Kähäri VM, Westermarck J. CIP2A inhibits PP2A in human malignancies. Cell. 2007 Jul 13;130(1):51-62. PMID: 17632056
January 2008
Kwang Seok Ahn

Ahn, K.S., Sethi, G., Krishnan, K. and Aggarwal, B.B. Gamma-tocotrienol inhibits nuclear factor-kappaB signaling pathway through inhibition of receptor-interacting protein and TAK1 leading to suppression of antiapoptotic gene products and potentiation of apoptosis. 2007.  J. Biol. Chem. 282:809-820. PMID: 17114179
July 2007
Young-Gun Yoo

Yoo, Y.G., Na, T.Y., Yang, W.K., Kim, H.J., Lee, I.K., Kong, G., Chung, J.H. and Lee, M.O.  2006. 6-Mercaptopurine, an activator of Nur77, enhances transcriptional activity of HIF-1alpha resulting in new vessel formation. Oncogene 26: 3823-3834.
January 2007
Ayyakkannu Ayyanan

Ayyanan A, Civenni G, Ciarloni L, Morel C, Mueller N, Lefort K, Mandinova A, Raffoul W, Fiche M, Dotto GP, Brisken C. Increased Wnt signaling triggers oncogenic conversion of human breast epithelial cells by a Notch-depedent mechanism. Proc. Natl. Acad. Sci. USA. 2006. 103:3799-3804.
July 2006
Vadim Budagian

Budagian V, Bulanova E, Orinska Z, Thon L, Mamat U, Bellosta P, Basilico C, Adam D, Paus R, Bulfone-Paus S. A promiscuous liaison between IL-15 receptor and Axl receptor tyrosine kinase in cell death control. EMBO J. 2005 Dec 21;24(24):4260-70. Epub 2005 Nov 24.
January 2006
Irina Kratchmarova

Irina Kratchmarova, Blagoy Blagoev, Mandana Haack-Sorensen, Moustapha Kassem, Matthias Mann1. Mechanism of Divergent Growth Factor Effects in Mesenchymal Stem Cell Differentiation. Science. 2005 Jun 3; 308(5727):1472-7.
July 2005
Maen Abdeirahim

Abdelrahim, M., Lui, S., and Safe, S. 2005. Induction of Endoplasmic Reticulum (ER)-Induced Stress Genes in Panc-1 Pancreatic Cancer Cells is Dependent on Sp Proteins. J Biol Chem. 280(16):16508-13
January 2005
J. L. Lavrrar

Lavrrar JL and Farnham PJ. 2004. The use of transient chromatin immunoprecipitation assays to test models for E2F1-specific transcriptional activation. J Biol. Chem. 2004 279:46343-46349.
July 2004
Masako Miura

Miura, M., Gronthos, S., Zhao, M., Lu, B., Fisher, LW., Robey, PG., and Shi, S. 2003. SHED: stem cells from human exfoliated deciduous teeth. PNAS USA. 100(10):5807-5812
January 2004
Sarah P. Thayer

Sarah P. Thayer, Pasca di Magliano, P., Heiser, P., Nielson, C., Roberts, D., Lauwers, G., Qi, Y., Gysin, S., Fernndez-del Castillo, C., Yajnik, V., Antoniu, B., McMahon, M., Warshaw, A., and Hebrok, M. 2003. Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis. Nature. 425:851-856
July 2003
Marina Macias-Silva

Marina Macias-Silva, Li, W., Leu, L.I., Crissey, S. M.A., and Taub, R. 2002. Up-regulated transcriptional repressors SnoN and Ski Bind Smad proteins to antagonize transforming growth factor- signals during liver regeneration. J. Biol. Chem. 277: 28483-28490.
January 2003
Nigel Carter

Carter, N., Nakamoto, T., Hirai, H., and Hunter, T. 2002. EphrinA1-induced cytoskeletal re-organization requires FAK and p130(cas). Nat. Cell Biol. 4: 565-573.
July 2002
A.S. Weinmann

Weinmann, A.S., Bartley, S.M., Zhang, T., Zhang, .MQ., and Farnham, P.J. 2001. Use of chromatin immunoprecipitation to clone novel E2F target promoters. Mol. Cell. Biol. 21: 6820-6832.
January 2002
Olivier Nicole

Olivier Nicole, Fabian Docagne, Carine Ali, Isabelle Margaill, Peter Carmeliet, Eric T. MacKenzie, Denis Vivien and Alain Buisson. 2001. The proteolytic activity of tissue-plasminogen activator enhances NMDA receptor-mediated signaling. Nature Medicine. 7: 59-64.
July 2001
Yan-Hong Zhang

Yan-Hong Zhang, Antoinette Heulsmann, M. Mehrdad Tondravi, Aditi Mukherjee, and Yousef Abu-Amer. 2001. Tumor Necrosis Factor- (TNF) Stimulates RANKL-induced Osteoclastogenesis via Coupling of TNF Type 1 Receptor and RANK Signaling Pathways. J. Biol. Chem. 276: 563-568.
January 2001
Giulia Guarguaglini

Giulia Guarguaglini, Luigina Renzi, Filippo D'Ottavio, Barbara Di Fiore, Martina Casenghi, Enrico Cundari, and Patrizia Lavia. 2000. Regulated Ran-binding Protein 1 Activity Is Required for Organization and Function of the Mitotic Spindle in Mammalian Cells in Vivo. Cell Growth & Differentiation Vol. 11: 455-465
July 2000
Hui Miao

Hui Miao, Elisabeth Burnett, Michael Kinch, Erin Simon, and Bingcheng Wang. 2000. Activation of EphA2 kinase suppresses integrin function and causes focal-adhesion-kinase dephosphorylation. Nature Cell Biology 2: 62-69.
January 2000
Hongwu Chen

Hongwu Chen, Richard J. Lin, Wen Xie, Damien Wilpitz, and Ronald M. Evans. 1999. Regulation of Hormone-Induced Hyperacetylation and Gene Activation via Acetylation of an Acetylase. Cell 98: 675-686.
July 1999
Jan Karlseder

Jan Karlseder, Dominique Broccoli, Yumin Dai, Stephen Hardy and Titia de Lange. 1999. p53- and ATM-Dependent Apoptosis Induced by Telomeres Lacking TRF2. Science 283: 1321-1325.
January 1999
Shoji Yamaoka

Shoji Yamaoka, Gilles Courtois, Christine Bessia, Simon T. Whiteside, Robert Weil, Fabrice Agou, Heather E. Kirk, Robert J. Kay, and Alain Isral. 1998. Complementation Cloning of NEMO, a Component of the IB Kinase Complex Essential for NF-B ActivationK. Cell 93: 1231-1240.
July 1998
Robin X. Luo

Robin X. Luo, Antonio A. Postigo, and Douglas C. Dean. 1998. Rb Interacts with Histone Deacetylase to Repress Transcription. Cell 92: 463-473.
January 1998
Catherine H. Regnier

Catherine H. Regnier, Ho Yeong Song, Xiong Gao, David V. Goeddel, Zhaodan Cao, and Mike Rothe. 1997. Identification and Characterization of an IB Kinase. Cell 90: 373-383.
July 1997
Frank S. Lee

Jeremiah Hagler, Zhigian J. Chen, and Tom Maniatis. 1997. Activation of the IB Kinase Complex by MEKK1, a Kinase of the JNK Pathway. Cell 88: 213-222.
January 1997
Daniel J. Van Antwerp

Daniel J. Van Antwerp, Seamus J. Martin, Tal Kafri, Douglas R. Green and Inder M. Verma. 1996. Suppression of TNF--induced apoptosis by NF-B. Science 274: 787-789.
July 1996
Shuqian Jing

Shuqian Jing, Duanzhi Wen, Yanbin Yu, Paige L. Holst, Yi Luo, Mei Fang, Rami Tamir, Laarni Antonio, Zheng Hu, Rod Cupples, Jean-Claude Louis, Sylvia Hu, Bruce W. Altrock and Gary M. Fox. 1996. GDNF-induced activation of the Ret protein tyrosine kinase is mediated by GDNFR-, a novel receptor for GDNF. Cell 85: 1113-1124.
January 1996
Omar A. Coso

Omar A. Coso, Mario Chiariello, Jin-Chen Yu, Hidemi Teramoto, Piero Crespo, Ningzhi Xu, Toru Miki, and J. Silvio Gutkind. 1995. The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway. Cell 81: 1137-1146.
July 1995
David D. Schlaepfer

David D. Schlaepfer, Steven K. Hanks, Tony Hunter, and Peter van der Geer. 1994. Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase. Nature 372: 786-791
January 1995
Ellen Freed

Ellen Freed, Marc Symons, Susan G. Macdonald, Frank McCormick, and Rosamaria Ruggieri. 1994. Binding of 14-3-3 proteins to the protein kinase Raf and effects on its activation. Science 265: 1713-1716.
Win the January 2017 Santa Cruz Investigator Award: Send us your papers.
To apply for an Investigator Award, submit your accepted paper (1st author) referencing the use of any Santa Cruz product along with a review of the product. All entrants will receive 350 Cruz Credits™ for submitting a paper.
In addition to submitting a paper a review must also be submitted.
The winner will receive 5000 Cruz Credits™, which can be used as credits towards future product purchases or special promotions (see Cruz Credit™ Program). The winner will be selected from papers published within 12 months before the award date.