epitope mapping within an internal region of ZDHHC20 of human origin
recommended for detection of ZDHHC20 of mouse and human origin by WB, IF and ELISA; also reactive with additional species, including canine, bovine and porcine
TransCruz reagent for Gel Supershift and ChIP applications, sc-84668 X, 200 µg/0.1 ml
ZDHHC20 Background Information Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZDHHC20 (zinc finger, DHHC-type containing 20) is a 365 amino acid multi-pass membrane protein that contains one DHHC-type zinc finger and is thought to function as a palmitoyltransferase, catalyzing the transformation of palmitoyl-CoA and a cysteine-conjugated protein to an S-palmitoyl protein and free CoA. In response to DNA damage, ZDHHC20, which exists as multiple alternatively spliced isoforms, may be phosphorylated by ATM or ATR. The gene encoding ZDHHC20 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome.
