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- rabbit polyclonal IgG, 200µg/ml
- epitope mapping within an internal region of GPR30 of human origin
- recommended for detection of GPR30 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including canine and porcine
- blocking peptide, sc-48524 P
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Conditions Générales
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GPR30 Background Information
G protein-coupled receptors (GPCRs), also designated seven transmembrane (7TM) receptors and heptahelical receptors, are a protein family which interact with G proteins (heterotrimeric GTPases) to synthesize intracellular second messengers such as diacylglycerol, cyclic AMP, inositol phosphates, and calcium ions. Their diverse biological functions range from vision and olfaction to neuronal and endocrine signaling and are involved in many pathological conditions. G protein receptor 30 (GPR30), also designated chemokine receptor-like 2 (CMKRL2), is a 375-amino acid protein orphan GCPR. GRP30 is an intracellular transmembrane estrogen receptor localized to the endoplasmic reticulum which binds estrogen and estrogen derivatives. |
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GPR30 (K-19)-R
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GPR30 (K-19)-R: sc-48524-R. Western blot analysis of GPR30 expression in MCF7 whole cell lysate. GPR30 (K-19)-R: sc-48524-R. Western blot analysis of GPR30 expression in SK-BR-3 whole cell lysate. |
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