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- goat polyclonal IgG, 200 µg/ml
- epitope mapping at the N-terminus of EBP2 of human origin
- recommended for detection of EBP2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including canine, bovine and porcine
- blocking peptide, sc-46316 P
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Conditions Générales
Accessoires recommandés:
(Cliquez sur l'application voulue)
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| Espèce |
Nom du Gène |
Gene ID |
Localisation chromosomique |
Numéro d'accession de l'isoforme (ARNm) |
Numéro d'accession de la protéine |
Numéro OMIM™ |
| Humain |
EBNA1BP2 |
10969 |
1p34.2 |
NM_006824 |
Q99848
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n/a |
| Souris |
Ebna1bp2 |
69072 |
4 D2.1 |
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Q9D903
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Non disponible |
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EBP2 Background Information
The replication and stable maintenance of latent Epstein-Barr virus DNA episomes in human cells requires only one viral protein, Epstein-Barr nuclear antigen 1 (EBNA1). EBNA1 binding protein 2, also designated p40/EBP2, is a nuclear protein required for the processing of the 27S pre-rRNA. EBP2 is highly conserved across species and is ubiquitously expressed in human tissues, especially myelogenous leukemia K-562. EBP2 specifically interacts with EBNA1, supporting the long-term maintenance of Epstein-Barr virus plasmids in human cells. The EBNA1-EBP2 complex is important for the stable segregation of Epstein-Barr virus episomes during cell division. |
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EBP2 (N-13)
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EBP2 (N-13): sc-46316. Western blot analysis of EBP2 expression in HeLa nuclear extract. Kindly provided by Dr. Nobuaki Kikyo, Stem Cell Institute, University of Minnesota.
EBP2 (N-13): sc-46316. Immunofluorescence staining of paraformaldehyde-fixed HeLa cells showing Hoechst nuclear staining (A) and nucleolar localization (B). Kindly provided by Dr. Nobuaki Kikyo, Stem Cell Institute, University of Minnesota.
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