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- mouse monoclonal IgG2b, 200µg/ml
- raised against amino acids 513-775 mapping at the C-terminus of GlnRS of human origin
- recommended for detection of GlnRS of human origin by WB, IP, IF and ELISA
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Conditions Générales
Accessoires recommandés:
(Cliquez sur l'application voulue)
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| Espèce |
Nom du Gène |
Gene ID |
Localisation chromosomique |
Numéro d'accession de l'isoforme (ARNm) |
Numéro d'accession de la protéine |
Numéro OMIM™ |
| Humain |
QARS |
5859 |
3p21.31 |
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P47897
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603727 |
| Souris |
Qars |
97541 |
9 F2 |
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NP_598555
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Non disponible |
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GlnRS Background Information
Aminoacyl-tRNA synthetases function to catalyze the aminoacylation of tRNAs by their corresponding amino acids, thus linking amino acids with tRNA-contained nucleotide triplets. GlnRS (Glutaminyl-tRNA synthetase), also known as QARS, is a 775 amino acid member of the class-I aminoacyl-tRNA synthetase family. Localized to the cytoplasm, GlnRS is part of a multi-protein complex composed of nine aminoacyl-tRNA synthetases that are specific for nine amino acids, namely Arg, Asp, Glu, Gln, Ile, Leu, Lys, Met and Pro. In this complex, GlnRS functions to catalyze the ATP-dependent conversion of L-glutamine (Gln) and tRNA(Gln) to Gln-tRNA(Gln). While GlnRS is used to synthesize Gln-tRNA(Gln) in many eukaryotic cells, prokaryotes and organelles, such as mitochondria and chloroplasts, can synthesize Gln-tRNA(Gln) in a two step process involving misacylation and amidation reactions. |
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GlnRS (F-4)
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GlnRS (F-4): sc-166241. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.
GlnRS (F-4): sc-166241. Western blot analysis of GlnRS expression in non-transfected 293T: sc-117752 (A), human GlnRS transfected 293T: sc-113657 (B) and HeLa (C) whole cell lysates. |
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