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- mouse monoclonal IgG1, 200µg/ml
- raised against amino acids 873-1172 mapping at the C-terminus of Laminin β-3 of human origin
- recommended for detection of Laminin β-3 of human origin by WB, IP, IF and ELISA
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Conditions Générales
Accessoires recommandés:
(Cliquez sur l'application voulue)
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| Espèce |
Nom du Gène |
Gene ID |
Localisation chromosomique |
Numéro d'accession de l'isoforme (ARNm) |
Numéro d'accession de la protéine |
Numéro OMIM™ |
| Humain |
LAMB3 |
3914 |
1q32.2 |
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Q13751
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226700 |
| Souris |
Lamb3 |
16780 |
1 H6 |
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Q61087
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Non disponible |
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Laminin β-3 Background Information
The Laminins comprise a growing family of disulfide-linked heterotrimers consisting of three genetically distinct polypeptide chains, designated å, ∫ and © (1–3). A major component of the basal lamina, Laminins play a crucial role in providing a scaffolding upon which tissues are assembled and which serves as a physical barrier separating specialized tissues (4,5). During embryogenesis and early development, cells migrate along basement membranes, which are required for the polarization of cells (6). At least eight Laminin isoforms have been described: å-1, å-2, å-3, ∫-1, ∫-2, ∫-3, ©-1 and ©-2 (7). Each isoform differs in the relative affinity with which it associates with individual Laminin receptors (7–9). |
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Laminin β-3 (A-6)
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Laminin β-3 (A-6): sc-133178. Western blot analysis of Laminin β-3 expression in SCC-4 whole cell lysate.
Laminin β-3 (A-6): sc-133178. Western blot analysis of Laminin β-3 expression in non-transfected 293T: sc-117752 (A), human Laminin β-3 transfected 293T: sc-177458 (B) and A-431 (C) whole cell lysates. Laminin β-3 (A-6): sc-133178. Western blot analysis of Laminin β-3 expression in non-transfected 293T: sc-117752 (A), human Laminin β-3 transfected 293T: sc-177459 (B) and A-431 (C) whole cell lysates. |
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