¡Bienvenido a Santa Cruz Biotechnology!
SCBT Home
Página Principal » Research Products » Primary Antibodies: Mammalian » Kinasas y fosfatasas  » SIK Anticuerpos

SIK Anticuerpos

Presentamos HOVERcruz™,

un sistema único para la rápida identificación de SIK Anticuerpos. Desplace el puntero sobre los nombres de los productos de la tabla para ver los datos representativos de cada producto.

¡Chat en linea está disponible! (haga click aquí)

Nuestro sistema de chat en linea está disponible para contestar sus preguntas sobre pedidos y productos.

Vea tambiénSIK Antibodies incluyendo, SIK1, SIK2

NOMBRE DEL PRODUCTO NÚMERO DEL CATÁLOGO:ISOTIPOEPíTOPOAPLICACIONESESPECIESMENCIONESCLASIFICACIÓN
SIK1 (Y-20)sc-83754conejo IgGInternal (h)WB, IP, IF, IHC(P), ELISAm, r, h, e, b, a
SIK1 (H-40)sc-366014conejo IgG241-280 (h)WB, IP, IF, ELISAm, r, h
SIK1 (E-22)sc-134002conejo IgGN/AWB, IP, IF, IHC(P), ELISAhumano
SIK2 (C-18)sc-33074cabra IgGC-terminal (h)WB, IP, IF, ELISAm, r, h, e, b
SIK2 (Y-19)sc-33073cabra IgGC-terminal (h)WB, IF, ELISAm, r, h

SIK silenciadores génicos siARN, Plásmidos de shARN y Partículas Lentivirales shRNA incluyendo:

siRNAsPlásmidos shRNAshRNA partículas antiviralesMENCIONESCLASIFICACIÓN
Sik siRNA (m): sc-153465Sik shRNA Plasmid (m):
sc-153465-SH		Sik shRNA (m)
Partículas Lentiviral  :sc-153465-V
Sik siRNA (m2): sc-270371Sik shRNA Plasmid (m2):
sc-270371-SH		Sik shRNA (m2)
Partículas Lentiviral  :sc-270371-V
SIK1 siRNA (h): sc-91428SIK1 shRNA Plasmid (h):
sc-91428-SH		SIK1 shRNA (h)
Partículas Lentiviral  :sc-91428-V
SIK1 siRNA (canine): sc-270182SIK1 shRNA Plasmid (canine):
sc-270182-SH		SIK1 shRNA (canine)
Partículas Lentiviral  :sc-270182-V
SIK2 siRNA (m): sc-44365SIK2 shRNA Plasmid (m):
sc-44365-SH		SIK2 shRNA (m)
Partículas Lentiviral  :sc-44365-V
SIK2 siRNA (h): sc-44364SIK2 shRNA Plasmid (h):
sc-44364-SH		SIK2 shRNA (h)
Partículas Lentiviral  :sc-44364-V

The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. SIK1 (salt-inducible kinase 1), also known as SNF1LK or MSK, is a 783 amino acid protein that contains one UBA domain and one protein kinase domain and belongs to the Ser/Thr protein kinase family. Localized to both the nucleus and the cytoplasm, SIK1 uses magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of target proteins and is thought to be important for the early stages of skeletal muscle growth and myocardial cell differentiation. Additionally, SIK1 has a potential role in regulation of the G2/M cell cycle transition, as well as in inhibitory control of CREB protein function. SIK2 is a ubiquitously expressed protein and is rapidly upregulated after a hormone-regulated form of Qin is activated. in vitro kinase tests demonstrate that SIK2 is capable of autophosphorylation. Elevated levels of SIK2 transcripts are also observed in Src-transformed cells, suggesting that Src and Qin share some targets.