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SC35 Anticuerpos

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Vea tambiénSC35 Antibodies incluyendo, SRp46

NOMBRE DEL PRODUCTO NÚMERO DEL CATÁLOGO:ISOTIPOEPíTOPOAPLICACIONESESPECIESMENCIONESCLASIFICACIÓN
SC35 (D-18)sc-10250cabra IgGN-terminal (h)WB, IP, IF, ELISAm, r, h, c, b, p, a1
SC35 (E-16)sc-10252cabra IgGN-terminal (h)WB, IP, IF, ELISAm, r, h, c, b, p, a1
SC35 (N-15)sc-10249cabra IgGN-terminal (h)WB, IF, ELISAm, r, h, c, b, p, a
SC35 (Y-16)sc-10251cabra IgGInterna (h)WB, IF, ELISAm, r, h, c, b, p, a2
SC35/SRp46 (H-55)sc-28720conejo IgG1-55 (h)WB, IP, IF, ELISAm, r, h, c, b, p, a

FosfoespecíficosSC35Anticuerpos

NOMBRE DEL PRODUCTO NÚMERO DEL CATÁLOGO:ISOTIPOEPíTOPOAPLICACIONESESPECIESMENCIONESCLASIFICACIÓN
p-SC35 (SC-35)sc-53518ratón IgG1FL (h)WB, IP, IF, IHC(P)h,r2

SC35 silenciadores génicos siARN, Plásmidos de shARN y Partículas Lentivirales shRNA incluyendo:

siRNAsPlásmidos shRNAshRNA partículas antiviralesMENCIONESCLASIFICACIÓN
SC35 siRNA (h): sc-38317SC35 shRNA Plasmid (h):
sc-38317-SH
SC35 shRNA (h)
Partículas Lentiviral  :sc-38317-V
SC35 siRNA (m): sc-38318SC35 shRNA Plasmid (m):
sc-38318-SH
SC35 shRNA (m)
Partículas Lentiviral  :sc-38318-V

Pre-mRNA splicing enhancer elements are short RNA sequences capable of activating weak splice sites in nearby introns that are required for accurate splice site recognition and the control of alternative splicing. Splicing enhancer elements contain specific binding sites for serine/arginine (SR)-rich splicing factors, which include SC35, 9G8, SRp20 and SF2/ASF. The family of SR factors all contain one or more RNA recognition motifs (RRM) and an arginine/serine (RS)-rich domain. They are not only essential for constitutive splicing but also regulate splicing in a concentration-dependent manner by influencing the selection of alternative splice sites. The majority of SR proteins, including SC35 and SRp40, are confined to the nucleus, while SF2/ASF, SRp20 and 9G8 are continuously shuttled between the nucleus and the cytoplasm and contribute to mRNA transport. The activity of SR proteins in regulated splicing is antagonized by members of the hnRNP A/B family of proteins, which induce drastic shifts in the selection of splicing sites. An additional SR-associated protein, p32, tightly associates with SR factors and preferentially inhibits ASF/SF2 functioning as both a splicing enhancer and splicing repressor protein by preventing the stable interaction of ASF/SF2 and RNA.